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Additional file 3 of Metabolic modeling of microbial communities in the chicken ceca reveals a landscape of competition and co-operation

2025· article· W7107994296 on OpenAlexaff

Bibliographic record

VenueFigshare · 2025
Typearticle
Language
FieldBiochemistry, Genetics and Molecular Biology
TopicGut microbiota and health
Canadian institutionsUniversity of AlbertaSickKids FoundationHospital for Sick ChildrenUniversity of Toronto
Fundersnot available
KeywordsJaccard indexCompetition (biology)CentroidMetagenomicsSimilarity (geometry)SyntenySample (material)Genome

Abstract

fetched live from OpenAlex

Supplementary Material 3. Supplementary Figure 3. Characteristics of 237 reconstructed MAGs. A-C. Boxplots showing beta-dispersion analysis results - the distances from each sample to the centroid of its respective group (HB or NB). Lower values indicate samples within that group are more similar to each other, while higher values indicate greater within-group variability. The significant differences in dispersion between HB and NB communities (particularly for reaction and pathway abundance) reveal that NB communities exhibit more variable metabolic profiles than HB communities, suggesting that Bacteroides presence may constrain metabolic variability. Distances were calculated from: (A) PCoA based on reaction content (top: Jaccard distances for presence/absence; bottom: Bray-Curtis dissimilarities for abundance-weighted data); (B) PCoA based on pathway content (top: Jaccard distances; bottom: Bray-Curtis dissimilarities); and (C) taxonomic composition at the family level. (). Significance determined using beta-dispersion (TukeyHSD) test. * - p-value < 0.05, ** - p-value <0.01, *** - p-value < 0.001. D. Major characteristics of 237 MAGs reconstructed in this study: completeness, contamination, N50 and genome size.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Dataset · Consensus signal: Dataset
Teacher disagreement score0.750
Threshold uncertainty score0.357

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.007
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.003
Science and technology studies0.0010.000
Scholarly communication0.0020.002
Open science0.0020.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.7500.187

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.261
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreDataset

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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