Factors affecting the glycemic index of fruits and its application in fruits choice of type 2 DM patients

目錄 中文摘要 I 英文摘要 III 目錄 IV 表目次 VIII 圖目次 IX 第一章 前言 1 第二章 文獻回顧 3 第一節 第 2 型糖尿病的飲食控制與治療 3 第二節 昇糖指數 5 一、 GI 概論及其定義 5 二、 GI 值與糖尿病 7 三、 GI 值與胰島素 7 四、 GI 值與血脂 8 第三節 餐後血糖的重要性 10 第四節 水果的角色 12 一、 單醣及雙醣 12 二、 膳食纖維 13 三、 甜度與糖度 14 第五節 -GLUCOSIDASE INHIBITOR之介紹 15 第三章 動機與目的 16 第四章 實驗設計與研究方法 18 第一節 水果 GI 值測定及其影響因子之分析 20 一、 受試者之召募與條件 20 二、 水果糖度之測定與篩選 22 三、 水果 GI 值之測定 24 四、 相關因子之分析 25 第二節 探討第2型糖尿病患者對選擇水果的認知及水果 GI 值之分析 28 一、 問卷調查 28 二、 水果 GI 的測定 28 第五章 統計分析 31 第六章 實驗結果 32 第一節 實驗第一部份 32 一、 受試者基本資料 32 二、 各種水果的測定時間及基本特性 2 三、 水果 GI 值及其相關因子之關聯性 5 第二節 實驗第二部份 7 一、 第 2 型糖尿病患者問卷調查結果 7 二、 第 2 型糖尿病患者基本資料 10 三、 第 2 型糖尿病患者水果 GI 值之測定 12 第三節 健康受試者與第 2 型糖尿病患者比較 14 一、 餐後血糖反應、水果之 PII 及 GI 值的結果比較 14 二、 第一部份水果 GI 值及第二部份問卷結果比較 17 第七章 討論 18 第一節 水果 GI 值與相關因子之關聯性 18 一、 醣類與 GI 值之相關性 18 二、 膳食纖維與 GI 值之相關性 19 三、 α-glucosidase inhibitory activity 與 GI 值之關聯性 21 四、 不同季節對水果 GI 值的影響 22 五、 香蕉中澱粉的含量對血糖之影響 22 第二節 健康受試者與第 2 型糖尿病患者之比較 24 一、 健康受試者與第 2 型糖尿病患者餐後血糖反應之比較 24 二、 健康受試者與第 2 型糖尿病患者之水果的 PII 及 GI 值比較 25 三、 第 2 型糖尿病患者之水果選擇認知情形與健康受試者之水果 GI 值比較 25 第三節 糖度與甜度 27 第四節 臨床應用 28 第八章 結論 29 第九章 參考資料 30 附錄一 研究計畫執行許可書 38 附錄二 受試者知情同意書 39 附錄三 第 2 型糖尿病患者之問卷調查 44 附錄四 第 2 型糖尿病患者之綜合問卷 47 表目次 表一、健康受試者基本資料 42 表二、各種水果測定的月份 44 表三、水果基本特性 45 表四、第 2 型糖尿病患者基本資料 52 表五、第 2 型糖尿病患者水果 GI 值之測定 54 表六、健康受試者與第 2 型糖尿病患者之水果的 PII 值 57 圖目次 圖 一、各種水果的糖度 32 圖 二、水果 GI 值及其相關因子之關聯性 47 圖 三、第 2 型糖尿病患者認為最可吃之水果排序 49 圖 四、第 2 型糖尿病患者認為最不可吃之水果排序 50 圖 五、第 2 型糖尿病患者與健康受試者之水果的餐後血糖反應曲線 56 食品工業發展研究所與屏東科技大學 (1988) 台灣地區食品營養成份資料庫，pp.94-113，行政院衛生署，台北市。 Abdulrhman M, El-Hefnawy M, Hussein R, El-Goud AA (2009) The glycemic and peak incremental indices of honey, sucrose and glucose in patients with type 1 diabetes mellitus: effects on C-peptide level-a pilot study. Acta Diabetol 26 [Epub ahead of print]. American Diabetes Association (2008) Nutrition recommendations and interventions for diabetes: a position statement of the American Diabetes Association. Diabetes Care 31: S61-78. Atkinson FS, Foster-Powell K, Brand-Miller JC (2008) International tables of glycemic index and glycemic load values: 2008. Diabetes Care 31: 2281-3. Belzer LM, Smulian JC, Lu SE, Tepper BJ (2009) Changes in sweet taste across pregnancy in mild gestational diabetes mellitus: relationship to endocrine factors. Chem Senses 34: 595-605. Brennan CS (2005) Dietary fibre, glycaemic response, and diabetes. Mol Nutr Food Res 49: 560-70. Chandalia M, Garg A, Lutjohann D, von Bergmann K, Grundy SM, Brinkley LJ (2000) Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus. N Engl J Med 342: 1392-8. Chareoansiri R, Kongkachuichai R (2009) Sugar profiles and soluble and insoluble dietary fiber contents of fruits in Thailand markets. Int J Food Sci Nutr 60: S126-39. Chong MF, Fielding BA, Frayn KN (2007) Mechanisms for the acute effect of fructose on postprandial lipemia. Am J Clin Nutr 85: 1511-20. Creutzfeldt W (1999) Effects of the alpha-glucosidase inhibitor acarbose on the development of long-term complications in diabetic animals: pathophysiological and therapeutic implications. Diabetes Metab Res Rev 15: 289-96. Davidson MH, McDonald A (1988) Fibre: forms and functions. Nutr. Res 18: 617–24. DeFronzo RA (1988) The Triumvirate: p-cell, muscle, liver: a collusion responsible for NIDDM. Diabetes 37: 667-87. DeFronzo RA (2004) Pathogenesis of type 2 diabetes mellitus. Med Clin North Am 88: 787-835. Du H, van der A DL, van Bakel MM, van der Kallen CJ, Blaak EE, van Greevenbroek MM, Jansen EH, Nijpels G, Stehouwer CD, Dekker JM, Feskens EJ (2008) Glycemic index and glycemic load in relation to food and nutrient intake and metabolic risk factors in a Dutch population. Am J Clin Nutr 87: 655-61. Englyst KN, Liu S, Englyst HN (2007) Nutritional characterization and measurement of dietary carbohydrates. Eur J Clin Nutr 61: S19-39. Hallfrisch J (1990) Metabolic effects of dietary fructose. FASEB J 4: 2652-60. Harbis A (2004) Glycemic and insulinemic meal responses modulate postprandial hepatic and intestinal lipoprotein accumulation in obese, insulin-resistant subjects. Am J Clin Nutr 80: 896–902. Harris PJ, Tasman-Jones C, Ferguson LR (2000) Effects of two contrasting dietary fibres on starch digestion, short-chain fatty acid production and transit time in rats. J. Sci. Food Agric 80: 2089–95. Higgins JA, Brand Miller JC, Denyer GS (1996) Development of insulin resistance in the rat is dependent on the rate of glucose absorption from the diet. J Nutr 126: 596-602. Hirsch IB, Brownlee M (2005) Should minimal blood glucose variability become the gold standard of glycemic control? J Diabetes Complications 19: 178-81. Holman RR, Paul SK, Bethel MA, Matthews DR, Neil HA (2008) 10-year follow-up of intensive glucose control in type 2 diabetes. N Engl J Med 359: 1577-89. Jenkins DJ, Wolever TM, Taylor RH, Barker H, Fielden H, Baldwin JM, Bowling AC, Newman HC, Jenkins AL, Goff DV (1981) Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr 34: 362-6. Jenkins DJ, Kendall CW, Augustin LS, Franceschi S, Hamidi M, Marchie A, Jenkins AL, Axelsen M (2002) Glycemic index: overview of implications in health and disease. Am J Clin Nutr 76: S266-73. Juvonen KR, Purhonen AK, Salmenkallio-Marttila M, Lähteenmäki L, Laaksonen DE, Herzig KH, Uusitupa MI, Poutanen KS, Karhunen LJ (2009 ) Viscosity of oat bran-enriched beverages influences gastrointestinal hormonal responses in healthy humans. J Nutr 139: 461-6. Karhunen LJ, Juvonen KR, Flander SM, Liukkonen KH, Lähteenmäki L, Siloaho M, Laaksonen DE, Herzig KH, Uusitupa MI, Poutanen KS (2010) A psyllium fiber-enriched meal strongly attenuates postprandial gastrointestinal peptide release in healthy young adults. J Nutr 140: 737-44. Kim YM, Jeong YK, Wang MH, Lee WY, Rhee HI (2005) Inhibitory effect of pine extract on alpha-glucosidase activity and postprandial hyperglycemia. Nutrition 21: 756-61. Krishnan S, Rosenberg L, Singer M, Hu FB, Djoussé L, Cupples LA, Palmer JR (2007) Glycemic index, glycemic load, and cereal fiber intake and risk of type 2 diabetes in US black women. Arch Intern Med 167: 2304-9. Laaksonen DE, Toppinen LK, Juntunen KS, Autio K, Liukkonen KH, Poutanen KS, Niskanen L, Mykkanen HM (2005) Dietary carbohydrate modification enhances insulin secretion in persons with the metabolic syndrome. Am J Clin Nutr 82: 1218-27. Lebovitz HE (1998) Postprandial hyperglycaemic state: importance and consequences. Diabetes Res Clin Pract 40: S27-8. Lee BM, Wolever TM (1998) Effect of glucose, sucrose and fructose on plasma glucose and insulin responses in normal humans: comparison with white bread. Eur J Clin Nutr 52: 924-8. Li X, Staszewski L, Xu H, Durick K, Zoller M, Adler E (2002) Human receptors for sweet and umami taste. Proc Natl Acad Sci USA 99: 4692-6. Marangoni F, Poli A (2008) The glycemic index of bread and biscuits is markedly reduced by the addition of a proprietary fiber mixture to the ingredients. Nutr Metab Cardiovasc Dis 18: 602-5. McKeown NM, Meigs JB, Liu S, Wilson PW, Jacques PF (2002) Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham Offspring Study. Am J Clin Nutr 76: 390-8. McKeown NM, Meigs JB, Liu S, Saltzman E, Wilson PW, Jacques PF (2004) Carbohydrate nutrition, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham Offspring Cohort. Diabetes Care 27: 538-46. Meyer KA, Kushi LH, Jacobs DR Jr, Slavin J, Sellers TA, Folsom AR (2000) Carbohydrates, dietary fiber, and incident type 2 diabetes in older women. Am J Clin Nutr 71: 921-30. Montori VM (2008) Should patients with type 2 diabetes focus on glycemic control to reduce their cardiovascular risk? Pol Arch Med Wewn 118: 502-7. Monzillo LU, Hamdy O (2003) Evaluation of insulin sensitivity in clinical practice and in research settings. Nutr Rev 61: 397-412. Murakami K, Sasaki S, Takahashi Y, Okubo H, Hosoi Y, Horiguchi H, Oguma E, Kayama F (2006) Dietary glycemic index and load in relation to metabolic risk factors in Japanese female farmers with traditional dietary habits. Am J Clin Nutr 83: 1161-9. Nalysnyk L, Hernandez-Medina M, Krishnarajah G (2010) Glycaemic variability and complications in patients with diabetes mellitus: evidence from a systematic review of the literature. Diabetes Obes Metab 12: 288-98. Nilsson AC, Ostman EM, Granfeldt Y, Bjorck IM (2008) Effect of cereal test breakfasts differing in glycemic index and content of indigestible carbohydrates on daylong glucose tolerance in healthy subjects. Am J Clin Nutr 87: 645-54. Parks EJ (2001) Effect of dietary carbohydrate on triglyceride metabolism in humans. J Nutr 131: S2772–4. Parks EJ, Skokan LE, Timlin MT, Dingfelder CS (2008) dietary sugar stimulate fatty acid synthesis in adults. J Nutr 138: 1039–46. Poppitt SD, van Drunen JD, McGill AT, Mulvey TB, Leahy FE (2007) Supplementation of a high-carbohydrate breakfast with barley beta-glucan improves postprandial glycaemic response for meals but not beverages. Asia Pac J Clin Nutr 16: 16-24. Ramli SB, Alkarkhi AF, Yong YS, Easa AM (2009) The use of principle component and cluster analyses to differentiate banana pulp flours based on starch and dietary fiber components. Int J Food Sci Nutr 60: S317-25. Riby JE, Fujisawa T, Kretchmer N (1993) Fructose absorption. Am J Clin Nutr 58: S748-53. Rioux LE, Turgeon SL, Beaulieu M (2009) Effect of season on the composition of bioactive polysaccharides from the brown seaweed Saccharina longicruris. Phytochemistry 70: 1069-75. Samanta A, Burden AC, Jones GR (1985) Plasma glucose responses to glucose, sucrose, and honey in patients with diabetes mellitus: an analysis of glycemic and peak incremental indices. Diabet Med 2:371–3 Schulze MB, Liu S, Rimm EB, Manson JE, Willett WC, Hu FB (2004) Glycemic index, glycemic load, and dietary fiber intake and incidence

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