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Record W7112811024

Les impacts de la chimiothérapie sur la fonction musculaire de l’enfant atteint de cancer

2025· dissertation· fr· W7112811024 on OpenAlexaboutno aff

Bibliographic record

VenueHAL (Le Centre pour la Communication Scientifique Directe) · 2025
Typedissertation
Languagefr
FieldMedicine
TopicChildhood Cancer Survivors' Quality of Life
Canadian institutionsnot available
Fundersnot available
KeywordsObservational studyGeneralizability theoryMuscle strengthChemotherapyCancerQuality of life (healthcare)Muscle architectureMEDLINEClinical trial
DOInot available

Abstract

fetched live from OpenAlex

Background: Anticancer treatments, especially chemotherapy, can negatively impact muscular function in children cancer. These alterations may include loss of muscle mass, strength or joint flexibility. Objective : This literature review aimed to explore the effects of chemotherapy on muscular function in pediatric cancer patients. Method: A search was conducted in PubMed and Cochrane databases between September 2024 and March 2025. Four observational studies were selected : one case-control study, one cohort, one cross-sectional study, and one retrospective study. Risk of bias was assessed using the Newcastle-Ottawa Scale (NOS). Results: The included studies showed a tendency toward decreased muscle mass, strength and quality of life during or after chemotherapy. However, heterogeneity in methodology, small sample sizes and non-standardized tools limit the generalizability of the findings. Discussion: While a causal link between chemotherapy an impaired muscle function cannot be definitively established, this review highlights the importance of early physiotherapy involvement and systematic functional assessment. Further research is needed to strengthen the level of evidence on this issue.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.014
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.005
Threshold uncertainty score0.019

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.014
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.003
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.302
Teacher spread0.288 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueHAL (Le Centre pour la Communication Scientifique Directe)→Same topicChildhood Cancer Survivors' Quality of Life→French-language works237,207→