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Record W7113905018 · doi:10.1016/j.bspc.2025.109269

Exploring quantile graphs: A novel approach for classifying Parkinson’s disease-related events during the TUG test

2025· article· en· W7113905018 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueBiomedical Signal Processing and Control · 2025
Typearticle
Languageen
FieldNeuroscience
TopicEEG and Brain-Computer Interfaces
Canadian institutionsCentre for Movement Disorders
FundersFundação de Amparo à Pesquisa do Estado de São Paulo
KeywordsQuantileTest (biology)Quantile regressionReliability (semiconductor)Event (particle physics)

Abstract

fetched live from OpenAlex

Parkinson’s disease (PD) is a neurological disorder that impacts the central nervous system, leading to a progressive decline in motor functions, including symptoms like tremors and episodes of freezing. An important area of research has been the challenges posed by these freezing episodes, during which individuals suddenly halt and struggle to resume coordinated movements. Recent studies have utilized electroencephalography (EEG) to analyze PD; however, this method faces certain limitations, prompting the investigation of alternative and interdisciplinary approaches to obtain a more comprehensive understanding of EEG signals. A promising methodology involves the use of Quantile Graphs (QGs), which have demonstrated potential in differentiating patients with various medical conditions. However, they have yet to be applied to those with PD. This article aims to explore the application of QGs for quantifying differences in the brains of individuals affected by PD, thereby paving the way for the integration of this method into PD research. To achieve this goal, EEG data were collected from 18 channels across six PD patients, capturing three distinct events during the Timed Up and Go (TUG) test: normal walking, freezing of gait (FoG), and voluntary stop. The combination of the QG method with machine learning techniques was effective in distinguishing between FoG and non-FoG EEG events. The findings validated the utility of QG in analyzing complex and nonlinear signals, such as those produced by EEG recordings in individuals with PD.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.928
Threshold uncertainty score0.611

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.052
GPT teacher head0.268
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it