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Record W7114902966 · doi:10.1093/ehjcr/ytaf640

Case series of Type 1 Brugada pattern provoked by exercise: a role for diagnostic treadmill stress testing

2025· article· en· W7114902966 on OpenAlexaff

Bibliographic record

VenueEuropean Heart Journal - Case Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiac electrophysiology and arrhythmias
Canadian institutionsSt. Paul's HospitalVancouver Hospital and Health Sciences CentreUniversity of British ColumbiaRoyal Jubilee Hospital
Fundersnot available
KeywordsBrugada syndromeSeries (stratigraphy)Stress testing (software)ElectrocardiographyValue (mathematics)

Abstract

fetched live from OpenAlex

Background: gene, most implicated in heritable BrS, is found in only 20% of those who have the clinical phenotype seen with BrS. Establishing the diagnosis of BrS can be challenging as the electrocardiogram (ECG) pattern that is diagnostic for the syndrome is often transient. Typically, a pharmacological challenge using a Class 1 antiarrhythmic is used to provoke a Type 1 Brugada pattern on ECG that may otherwise be concealed. Case summary: We describe a case series of three unrelated patients who underwent an exercise treadmill test (ETT) according to standard Bruce protocol. Each patient demonstrated a Type 1 Brugada pattern most apparent in the early recovery phase immediately after peak exercise but not at baseline. Discussion: This case series highlights the value of ETT as a diagnostic aid for BrS. We suggest that ETT could be considered as a routine means of provoking a Brugada ECG pattern.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.034
Threshold uncertainty score0.668

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.284
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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