Gastrointestinal strictures in a pediatric patient with Satoyoshi syndrome
Bibliographic record
Abstract
We present a novel case of gastrointestinal strictures in a young girl with Satoyoshi syndrome (SS), highlighting multi-system features of alopecia universalis, painful muscle cramps with dystonia, aberrant growth velocity, and skeletal abnormalities. This case demonstrates an unusual pattern of patchy mucosal fibrosis throughout the gastrointestinal tract, alongside duodenal and rectal strictures, with only mild inflammation. While serial endoscopic dilatations and systemic corticosteroids resulted in symptomatic benefit, trial of a Janus kinase-1 inhibitor (upadacitinib) did not prevent the development of a subsequent rectal stricture. As the pathogenesis of SS remains undefined and treatment modalities are experimental, the observed fibrostenotic complications may point towards new underlying disease mechanisms.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".