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Record W7117125270 · doi:10.1097/pq9.0000000000000861

A Quality Improvement Project to Limit Perioperative Transfusion During Craniofacial Surgery in Infants and Children

2025· article· en· W7117125270 on OpenAlexaff
Grace C. Parizek, Annie Drapeau, Jonathan Pindrik, Gregory D. Pearson, Joseph D. Tobias, Ashley Smith

Bibliographic record

VenuePediatric Quality and Safety · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCraniofacial Disorders and Treatments
Canadian institutionsUniversity of Manitoba
Fundersnot available
KeywordsCranial vaultPerioperativeBlood transfusionCraniofacial surgeryCraniosynostosisCraniofacial

Abstract

fetched live from OpenAlex

Introduction: Open surgery for craniosynostosis in infants and children is frequently associated with significant intraoperative blood loss and the need for allogeneic transfusion therapy. A lack of consensus at our institution led to inconsistent transfusion therapy during open cranial vault remodeling. We sought to address this through a multidisciplinary quality improvement approach to decrease variability in transfusion practices. Methods: A streamlined intraoperative transfusion algorithm, from the moment the patient was evaluated in the preoperative holding area on the day of surgery through their departure from the postanesthesia care unit, was implemented during quarter 1 of 2021. We aimed to decrease the percentage of intraoperative transfusions administered at hemoglobin (Hgb) levels greater than 7.5 g/dL in stable patients without massive bleeding undergoing open craniosynostosis surgery from 40% in January 2021 to 0% by December 2023. Results: From January 2018 to December 2023, 118 pediatric patients underwent open cranial vault remodeling for craniosynostosis. Before the implementation of the protocol in quarter 1 of 2021, open cranial vault reconstruction (CVR) intraoperative transfusion rates in cases where the threshold was not met (Hgb >7.5 g/dL) were 32%. After protocol implementation, open CVR intraoperative transfusion rates that did not meet the threshold averaged 5%. Conclusions: In this quality improvement project, we decreased transfusion rates for patients with Hgb greater than 7.5 g/dL from 32% to 5% during 3 years. We have successfully developed and implemented an intraoperative blood transfusion algorithm that is generalizable and requires minimal human and material resources.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.022
Threshold uncertainty score0.665

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.304
Teacher spread0.290 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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