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Record W7117125618 · doi:10.14740/jem1582

Prevalence of Diabetic Peripheral Neuropathy and Its Association With Vitamin B12 Deficiency and Health-Related Quality of Life

2025· article· en· W7117125618 on OpenAlexvenueaboutno aff
Berniza Calderon, Manuel Soto, Sahel Ghazanfari, Janet Velez, Sherezade Hasbun

Bibliographic record

VenueJournal of Endocrinology and Metabolism · 2025
Typearticle
Languageen
FieldMedicine
TopicFolate and B Vitamins Research
Canadian institutionsnot available
Fundersnot available
KeywordsPeripheral neuropathyDiabetes mellitusQuality of life (healthcare)Diabetic neuropathyContext (archaeology)Vitamin B12VitalityPsychological intervention

Abstract

fetched live from OpenAlex

Background: The aim of the study was to determine the prevalence of diabetic peripheral neuropathy and vitamin B12 deficiency, their associated factors, and impact on health-related quality of life in a sample from the Dominican Republic. Methods: A total of 367 patients with diabetes were recruited. The Toronto Clinical Scoring System (TCSS) was used to evaluate the presence of neuropathy symptoms, while the 36-Item Short Form Health Survey (SF-36) was used to assess health-related quality of life. Results: Of the participants, 33.5% had neuropathy according to TCSS scores. Only one participant reported having a previous diagnosis of neuropathy. Factors associated with neuropathy were age, chronic renal insufficiency, and history of stroke. The prevalence of vitamin B12 deficiency was 4.5%, and no association was found with neuropathy. The presence of neuropathy significantly affected (P < 0.05) all physical dimensions of the SF-36 and the vitality dimension. Factors associated with the Physical Component Score (PCS) were age, neuropathy, and total number of comorbidities; factors associated with Mental Component Score (MCS) were age, sex, and being widowed. Conclusions: The prevalence of neuropathy was high and its impact on QoL was significant. Almost none of the patients in which neuropathy was detected had a previous diagnosis. Considering this, the development of awareness and prevention interventions among both doctors and patients in the Dominican context is of utmost importance.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.014
Threshold uncertainty score0.028

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.325
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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