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Record W7117241433 · doi:10.1002/alz70857_103108

Bilingualism and cognitive reserve: Preserving cortical thickness in aging individuals

2025· article· en· W7117241433 on OpenAlexaff
Tanya Dash, Yves Joanette, Ana‐Inès Ansaldo

Bibliographic record

VenueAlzheimer s & Dementia · 2025
Typearticle
Languageen
FieldNeuroscience
TopicNeurobiology of Language and Bilingualism
Canadian institutionsDouglas Mental Health University InstituteCanadian Institutes of Health ResearchUniversité de MontréalUniversity of Alberta
Fundersnot available
KeywordsCognitive reserveNeuroscience of multilingualismCognitionFunction (biology)Cognitive agingExecutive functions

Abstract

fetched live from OpenAlex

BACKGROUND: This study investigates the relationship between bilingualism, cognitive reserve, and cortical thickness in aging bilingual individuals. It explores the potential role of bilingualism in preserving brain structure against age-related decline. Cognitive reserve was evaluated using established measures of bilingualism (Dash et al., 2022) and the cognitive reserve index (CRIq; Nucci et al., 2012), accounting for gender effects to minimize bias. METHOD: A total of 79 bilingual individuals, aged 30 to 79 years, underwent neuroimaging analysis to assess cortical thickness using the FreeSurfer atlas. Partial least squares regression (PLSR) was employed to examine the relationship between age, bilingualism, and cognitive reserve indicators (such as CRIq) and cortical thickness across several brain regions. RESULTS: The analysis revealed three latent variables (LVs) that elucidate key brain-behavior relationships: The first latent variable, primarily driven by age, was associated with cortical thinning in regions typically impacted by aging, including the bilateral middle temporal cortex, hippocampus, lateral orbitofrontal cortex, and inferior temporal cortex. The second latent variable, incorporating both age and CRIq as predictors, highlighted regions linked to cognitive control and sensory processing, such as the insula, thalamus, and superior frontal cortex, indicating a protective effect of cognitive reserve against age-related cortical thinning. The third latent variable, with bilingualism-related measures as the predictor, revealed preserved cortical thickness in regions associated with language and executive control, including the pars opercularis, orbitofrontal cortex, and inferior parietal cortex, suggesting that bilingualism may provide a neural shield against aging-related brain changes. CONCLUSION: These findings support the hypothesis that bilingualism and cognitive reserve contribute to the preservation of cortical thickness in key regions, particularly those involved in cognitive control, language, and executive functions. This study provides further evidence for the protective role of bilingualism in maintaining brain structure and function in aging, contributing to the broader understanding of cognitive reserve mechanisms.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.335
Teacher spread0.294 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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