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Low-level Laser Therapy in Knee Osteoarthritis: A Prospective Analytical Study

2025· article· en· W7117243342 on OpenAlexaboutno aff
V Sriram, Nrupathunga K K, L Sachin Patel

Bibliographic record

VenueJournal of Clinical Orthopaedics · 2025
Typearticle
Languageen
FieldMedicine
TopicLaser Applications in Dentistry and Medicine
Canadian institutionsnot available
Fundersnot available
KeywordsWOMACOsteoarthritisVisual analogue scaleRange of motionLow level laser therapyIsometric exerciseLaser therapyProspective cohort study

Abstract

fetched live from OpenAlex

Background/Aims: Osteoarthritis (OA) is the second common rheumatologic disorder and the most prevalent joint disease in India, affecting 20–40% of the population. Low-level laser therapy (LLLT) has been used to alleviate pain in musculoskeletal conditions. Despite the fact that LLLT is extensively used, the consequences from both experimental and medical research continue to be inconsistent. This study aims to assess the pain-relieving effectiveness of LLLT in patients with Kellgren–Lawrence Grade I and II knee OA, using the Visual Analog Scale (VAS) and the Western Ontario McMaster Osteoarthritis Index (WOMAC). Materials and Methods: The study was carried out at a tertiary care center in Bengaluru. Fifty patients were recruited primarily based on the following inclusion criteria: 1. Idiopathic knee OA 2. Grade I or II bilateral knee OA confirmed by X-ray 3. Average pain intensity of 40 or greater on a 100-mm VAS 4. Age: 45–65 years, of both sexes. Patients attended weekly therapy sessions. Each session included isometric quadriceps muscle contractions and 10 repetitions of active range of motion exercises for the knee joint, following a 5-min LLLT application. Results: On X-ray, 52% (22 patients) had Grade I OA knee, and 48% (20 patients) had Grade II OA knee. There was a significant reduction in VAS and WOMAC post-treatment scores compared to pre-treatment. Conclusion: OA is a long-term, degenerative condition that causes deterioration of joint tissues, resulting in excessive pain, stiffness, and restricted mobility. Treatment strategies for OA continue to be crucial for research. Our study suggests a widespread improvement in pain alleviation with LLLT. Further studies are needed to compare the efficacy of LLLT with other pain management strategies and explore combined treatment plans. Keywords: Low-level Laser, OA knee, VAS, WOMAC

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.060
GPT teacher head0.431
Teacher spread0.371 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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