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Record W7117306995 · doi:10.1038/s41545-025-00545-4

Development of an open-source process simulator for microalgae-based tertiary phosphorus recovery

2025· article· en· W7117306995 on OpenAlexaff
G. D. Kim, Hannah R. Molitor, Xinyi Zhang, Yalin Li, Brian D. Shoener, Stephanie Schramm, Eberhard Friedrich Morgenroth, Spencer Snowling, Elaine Hartnett, Ian Bradley, Ameet Pinto, Jeremy S. Guest

Bibliographic record

Venuenpj Clean Water · 2025
Typearticle
Languageen
FieldEnergy
TopicAlgal biology and biofuel production
Canadian institutionsHatch (Canada)
FundersOffice of Energy EfficiencyOffice of Energy Efficiency and Renewable EnergyU.S. Department of Energy
KeywordsEffluentPhosphorusSewage treatmentWastewaterProcess (computing)Biomass (ecology)NutrientActivated sludge model

Abstract

fetched live from OpenAlex

Microalgae-based tertiary wastewater treatment has the potential to meet stringent effluent phosphorus limits, with the added benefit of producing a marketable feedstock. However, without validated models embedded in process simulators, the industry lacks the tools to evaluate the benefits and trade-offs of integrating tertiary microalgal treatment with conventional wastewater systems. In this study, an updated lumped pathway metabolic model was developed to predict effluent phosphorus concentration and biomass yield in response to dynamic influent and varying environmental conditions. The model was implemented in QSDsan – an open-source, Python-based design/simulation platform. Global sensitivity analysis was performed to prioritize model parameters for calibration. The model was then calibrated and validated using batch experiments and continuous online monitoring data from a full-scale microalgae-based tertiary wastewater treatment plant. Overall, the QSDsan-based microalgae process simulator was able to predict effluent phosphorus within 0.02–0.04 mg-P·L-1, while also capturing general trends of state variables according to nutrient availability.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.008
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.264
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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