New Insights in Exercise for Arrhythmogenic Cardiomyopathy: A Narrative Review
Bibliographic record
Abstract
Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiac condition and an important cause of sudden cardiac death among athletes. ACM may result in ventricular dysfunction with a high rate of ventricular arrhythmia disproportionate to the degree of cardiac chamber dilatation or dysfunction. Although ACM is genetically mediated for the most part, exercise has been recognized as a key modulator in its prognosis and outcomes. Several knowledge gaps exist surrounding the interaction between this condition and exercise. ACM is a heterogeneous condition with certain genotype-phenotype correlations that may result in differential impact of exercise. In addition, ACM patients traditionally have been relegated to participate in only low-intensity exercise, but this advice lacks objectivity and clear definitions, and no safe exercise thresholds have been proposed. Finally, no consensus has been reached on which exercise advice is to be given for genotype-positive phenotype-negative family members. The aim of this review is to address these concerns, propose a practical approach for exercise prescription in ACM, and provide an up-to-date literature review of the impact of exercise on the various subtypes of ACM.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".