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Record W7117670719 · doi:10.1002/1545-5017.70083

mTOR Inhibition in the Management of Recurrent Metastatic Solid Pseudopapillary Tumor of the Pancreas

2025· article· en· W7117670719 on OpenAlexafffundabout
Gabrielle Herzenberg, Tariq A. Bhat, Veronika Csizmók, Yaoqing Shen, Gregor S. D. Reid, Chris A. Maxwell, Philipp F. Lange, Daniel J. Renouf, Jonathan W. Bush, Claire Gowdy, Hannah G. Piper, Marco A Marra, Janessa Laskin, S. Rod Rassekh, C. James Lim, Rebecca Deyell

Bibliographic record

VenuePediatric Blood & Cancer · 2025
Typearticle
Languageen
FieldMedicine
TopicPancreatic and Hepatic Oncology Research
Canadian institutionsCanadian Centre for Applied Research in Cancer ControlCanada's Michael Smith Genome Sciences CentreBC Cancer AgencyBC Children's HospitalUniversity of British Columbia
FundersBC Cancer FoundationGenome British Columbia
KeywordsPI3K/AKT/mTOR pathwayPancreasDiscovery and development of mTOR inhibitorsAccrualPancreatic cancerCancerHealth board

Abstract

fetched live from OpenAlex

MAM serves on Terry Fox Research Institute's (TFRI) Research Council, Network Council, Canadian Spectrum Working Group, Technology Working Group (co-chair), Open Accrual Working Group, Digital Health Discovery Platform (co-chair), and as co-lead of the BC Cancer Consortium, which receives and allocates TFRI funding. TFRI provides funding support to his research program and trainees. R.J.D. has served on an advisory board for Bayer Inc.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.346
Teacher spread0.324 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

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