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Record W7118066671 · doi:10.5281/zenodo.18131042

Application of Artificial Intelligence and Machine Learning in Drug Discovery and Development of Smart Drugs

2024· article· W7118066671 on OpenAlexaff
Niev Sanghvi, Ved Ravindra Prakash, Deep Atul Deshmukh, Kashvi Mandge, Sharayu Shivshankar Kore, Swaraj Bhongade

Bibliographic record

VenueZenodo (CERN European Organization for Nuclear Research) · 2024
Typearticle
Language
FieldMedicine
TopicArtificial Intelligence in Healthcare and Education
Canadian institutionsBishop's University
Fundersnot available
KeywordsDrug discoveryTransformative learningProcess (computing)Precision medicineKnowledge extractionBig data

Abstract

fetched live from OpenAlex

This research paper explores the application of artificial intelligence (AI) in drug discovery and smart medicine development, highlighting its transformative impact on healthcare. The paper examines how AI is significantly streamlining the drug development process by rapidly analyzing biological data, predicting drug-target interactions, and identifying promising drugs. It addresses important issues including how AI is revolutionizing drug discovery and smart medicine development, the benefits and limitations of AI in this field, and ethical concerns arising from its integration. In addition, the paper discusses the future prospects of AI-based smart medicines and their potential impact on patient outcomes. To provide practical insights, various Python-integrated solutions are presented, such as complex activity prediction with RandomForestClassifier, visualization of drug discovery time using AI compared to traditional methods, bias detection in datasets, data anonymization, and assessing the impact of AI-powered smart medicine on healthcare. These solutions illustrate how AI can improve the efficiency and effectiveness of smart medicine creation, while considering ethical principles and patient-centered care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.004
Threshold uncertainty score0.019

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.007
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0010.002
Scholarly communication0.0030.002
Open science0.0010.002
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.106
GPT teacher head0.340
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2024
Admission routes1
Has abstractyes

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