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Record W7118080542 · doi:10.47743/jpd.2025.32.1.974

INVESTIGATING THE INTERACTOME OF ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASES: AN INTEGRATIVE APPROACH USING MULTIPLE SOURCES OF EVIDENCE

2025· article· W7118080542 on OpenAlexaff
Sameer KHAN, Tim Xing

Bibliographic record

VenueJournal of Plant Development · 2025
Typearticle
Language
FieldBiochemistry, Genetics and Molecular Biology
TopicPlant Gene Expression Analysis
Canadian institutionsCarleton University
Fundersnot available
KeywordsInteractomeArabidopsis thalianaProtein–protein interactionArabidopsisSystems biologySignal transductionInteraction networkModel organism

Abstract

fetched live from OpenAlex

Arabidopsis thaliana mitogen-activated protein kinase (MPK) signaling network plays a role in various cellular processes. This study integrated protein-protein interaction, genetic interaction, and co-expression data from the STRING, BioGRID, and ATTED-II databases to provide a comprehensive dataset of interactions within the network. The key MPK network components from this set were identified and subjected to functional enrichment analysis, which revealed their involvement in diverse biological processes and pathways. This integrative approach, combining multiple sources of evidence, provides a comprehensive approach for understanding Arabidopsis thaliana MPK signaling network. The findings demonstrate the complex regulatory mechanisms that play a role in plant stress responses and development.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0040.002
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.065
GPT teacher head0.312
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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