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Record W7118617434 · doi:10.1093/eurheartj/ehaf1018

Cardiovascular adaptation to training load in endurance athletes: a longitudinal study

2025· article· en· W7118617434 on OpenAlexaff
Christophe Dausin, Sergio Ruiz-Carmona, Nicholas Cauwenberghs, Ruben De Bosscher, Evangelos Ntalianis, Tatiana Kuznetsova, Kristel Janssens, Amy Mitchell, Willem Vanderschueren, Olivier Ghekiere, Jan Bogaert, C VAN DE HEYNING, Lieven Herbots, H Heidbuchel, Rik Willems, André La Gerche, Guido Claessen, Peter Hespel, Paolo D’Ambrosio, Stephanie Rowe, Luke Spencer, Maria Brosnan, David Prior, Piet Claus, Kaatje Goetschalckx, Sofie Van Soest, Youri Bekhuis, Mathias Claeys, Rik Pauwels, Boris Delpire, J De Paepe, Tim Van Puyvelde, Daisy Thijs, Peter Vanvoorden, Bert Op’t Eijnde, Paul Van Herck, Bernard Paelinck, Haroun El Addouli, Hielko Miljoen, Kasper Favere, Dorien Vermeulen, Steven Dymarkowski, Tom Dresselaers, Dominique Hansen, Kristof Lefebvre, Adrian Elliott, Prashanthan Sanders, Jonathan Kalman, D Fatkin, Wim Van Hoolst

Bibliographic record

VenueEuropean Heart Journal · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiovascular Effects of Exercise
Canadian institutionsUniversity of Alberta
FundersNational Health and Medical Research CouncilVlaamse regeringFonds Wetenschappelijk OnderzoekMedical Research CouncilAustralian GovernmentBoston Scientific Corporation
KeywordsLongitudinal studyDuration (music)Endurance trainingAdaptation (eye)Training (meteorology)Cardiovascular health

Abstract

fetched live from OpenAlex

BACKGROUND AND AIMS: Prior studies on cardiac remodelling associated with exercise have relied on self-reported data of uncertain accuracy. In the present study, exercise duration and intensity were objectively quantified using heart rate (HR) monitors in athletes, and these metrics were correlated with cardiac magnetic resonance findings. METHODS: Young (16-23 years, n = 69) and middle-aged (45-70 years, n = 82) male endurance athletes with ≥80% of training sessions recorded via chest-worn HR monitors over 3 months were included. Training duration, session count, and intensity (classified into five HR zones and expressed as Edwards training impulse in arbitrary units) were analysed. Cardiac magnetic resonance measured indexed left/right ventricular volumes, ejection fraction, and left ventricular mass. RESULTS: Younger athletes trained more than older athletes [169 (127-209) vs 78 (49-114) hours; 23 129 (17 880-28 305) vs 12 620 (7168-17 607) arbitrary units; both P < .05] over a 3-month period. In all athletes, light-to-moderate-intensity training exceeded thresholds of >6 or >9 metabolic equivalent of tasks to describe intense activity. Training duration (r > .33, P < .05 for all) and Edwards training impulse (r > .29, P < .05 for all) correlated with cardiac dimensions, but the duration always outperformed intensity. Time spent in lower HR zones (1 and 2) correlated more with cardiac dimensions than higher-intensity training. Partial least squares analysis identified training duration in Zones 1&2 and 3 and age as key determinants of cardiac remodelling, whereas intensity was not a significant determinant of cardiac dimensions. CONCLUSIONS: Objective exercise quantification reveals new insights into cardiac remodelling, highlighting total exercise duration as a primary determinant of left/right ventricular volumes, independent of intensity. Traditional questionnaire-based methods may overlook these relationships.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.649
Threshold uncertainty score0.804

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.069
GPT teacher head0.323
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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