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Record W7120866699

Methods of attribute selection and principal component analysis: a comparative study

2017· dissertation· pt· W7120866699 on OpenAlexaboutno aff
Jovani Taveira de Souza

Bibliographic record

VenueInstitutional Repository of the Federal Technological University of Paraná (RIUT) (Federal University of Technology – Paraná) · 2017
Typedissertation
Languagept
FieldBiochemistry, Genetics and Molecular Biology
TopicGene expression and cancer classification
Canadian institutionsnot available
Fundersnot available
KeywordsPrincipal component analysisDimensionality reductionSelection (genetic algorithm)Support vector machineFeature selectionField (mathematics)Curse of dimensionalitySet (abstract data type)
DOInot available

Abstract

fetched live from OpenAlex

Neoplasm is a major challenge for researchers because of its high complexity. Despite advances in diagnosis, studies point out that in addition to data analysis, methods to optimize and aid the decision-making process are necessary. In this sense, the dimensionality reduction of data has contributed significantly, helping in this process, due to the large number of genes (attributes) compared to the number of samples (classes). This work, therefore, aims to provide a comparative study between two methods of dimensionality reduction, applied to three databases in the field of gene expression: LungCancer-Michigan, LungCancer-Ontario and LungCancer-Harvard, all related to lung cancer. The methods applied were: Attribute Selection and Principal Component Analysis (PCA), both used as a pre-processing step in Data Mining. The classification algorithms chosen were Naive Bayes, SVM, J48, 1-NN, 3-NN, 5-NN and 7-NN. Weka was used as a software for analyses procedures. A series of experiments was performed to evaluate the accuracy and applicability of the algorithms for both methods. As a result, significant advances in the hit rate (accuracy) of the classifiers involving the methods were evidenced, using Cross-Validation as the assessment criterion. The Wrapper approach, from the Attribute Selection method, obtained the best results for the three analyzed databases. The Principal Component Analysis method, even presenting lower hit rate, could not be ruled out. The Naive Bayes, SVM and 1-NN algorithms presented the best performance within the databases. The attributes (genes) which presented the highest frequency in the databases were denoted. Therefore, from the chosen subsets, these can be submitted to specific analyzes in order to direct more precise diagnoses.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.023
metaresearch head score (Gemma)0.037
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.023
Threshold uncertainty score0.121

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0230.037
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0080.011
Science and technology studies0.0010.001
Scholarly communication0.0030.003
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.304
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2017
Admission routes1
Has abstractyes

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