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Record W7123860706 · doi:10.1049/pbhe066e_ch9

Revolutionizing pathological assessments with privacy-centric machine learning models

2025· book-chapter· en· W7123860706 on OpenAlexaff
S. Shiva Prakash, Anu Tonk, Sailaja Manepalli, R. Revathi, K.V. Shahnaz, Roshan Nayak

Bibliographic record

VenueHealth Informatics · 2025
Typebook-chapter
Languageen
FieldComputer Science
TopicPrivacy-Preserving Technologies in Data
Canadian institutionsHorizon College and Seminary
Fundersnot available
KeywordsSupport vector machineHomomorphic encryptionInferenceConfidentialityCryptographyEncryptionScheme (mathematics)Medical imaging

Abstract

fetched live from OpenAlex

This study aims to explore the possibility of using fully homomorphic encryption (FHE) in conjunction with machine learning for private pathological evaluation. Specifically, we will look at how support vector machine (SVM) inference phases might be used to classify sensitive medical data. To make SVM inference on encrypted datasets easier to implement, a system is presented that makes use of the Cheon-Kim-Kim-Song (CKKS) FHE protocol. This architecture eliminates the need to decode data before analysis and guarantees the confidentiality of patient records. Further, a method for efficiently extracting features from medical images for use in vector representations is introduced. The system's performance and usefulness are supported by its examination on different datasets. Classification accuracy and performance are comparable to that of conventional, non-encrypted SVM inference; however, the suggested technique protects the CKKS scheme from known cryptographic assaults with a 128-bit security level. In a matter of seconds, the secure inference procedure is carried out. Cardiology, oncology, and medical imaging are just a few of the areas that could gain from FHE's improved security and efficiency in bioinformatics analyses, according to these results. The significant future implications of this research for privacy-preserving machine learning can pave the way for improvements in diagnostic processes, individualized medical treatments, and clinical investigations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Open science
Consensus categoriesOpen science
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.707
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0010.000
Scholarly communication0.0000.001
Open science0.0160.055
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.078
GPT teacher head0.310
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designTheoretical or conceptual
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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