Hypertrophic cardiomyopathy: From accidental diagnosis to sudden cardiac death prevention
Bibliographic record
Abstract
Hypertrophic cardiomyopathy is defined by the presence of increased thickness of the left ventricular wall, which cannot be explained only by abnormal loading conditions. This definition applies to children and adults and makes no "a priori "assumptions about etiology or myocardial pathology. Cellular architecture disorders, interstitial fibrosis, microvascular infarctions, play a role in the emergence of electrical instability, malignant ventricular arrhythmias that cause Sudden Cardiac Death in patients with HCM. Although most cases have a benign prognosis, identifying patients at a risk for Sudden Cardiac Death, requiring prophylactic therapy with ICD, is crucial and prioritized. With increasing awareness of the disease, lower-risk patients are now more frequently diagnosed, and more recent studies show that the annual Sudden Cardiac Death rate 0.5-1%, was not negligible, unfortunately among young and asymptomatic individuals. This paper presents a case of HCM, accidentally detected in a young adult, completed with ICD implantation in primary Sudden Cardiac Death prevention.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".