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Active Learning for Lesion Segmentation Using Contrastive Learning with Strong Augmentation

2025· article· W7126080695 on OpenAlexaff
Jianyuan Li, Xiong Luo, Boyu Wang

Bibliographic record

Venuenot available
Typearticle
Language
FieldComputer Science
TopicAI in cancer detection
Canadian institutionsWestern University
FundersNational Key Research and Development Program of ChinaNatural Science Foundation of Beijing MunicipalityNational Natural Science Foundation of China
KeywordsSegmentationActive learning (machine learning)Pattern recognition (psychology)AnnotationSelection (genetic algorithm)Image segmentationSampling (signal processing)

Abstract

fetched live from OpenAlex

Active learning effectively reduces annotation costs while enhancing model performance in medical image segmentation tasks. One-shot active learning presents a highly practical scenario where valuable samples for annotation are selected in a single round. However, current one-shot active learning methods predominantly rely on sampling selection methods based on global information. In contrast, focusing on the selection of features specific to local lesion regions would be more targeted and effective. In this work, we introduce a novel deep active learning framework specifically designed for pathological lesion segmentation tasks. To enable the model to effectively capture lesion-related regions of interest, we propose a strong augmentation strategy for image samples in self-supervised contrastive training. These strong augmentation samples are generated through cluster-based background subtraction using cluster projector, thereby emphasizing the features of the target lesion and improving the model's sensitivity to these areas. We utilize the Segment Anything Model as the base model to facilitate training and sample selection in a one-shot manner. Experimental results on two lesion segmentation datasets demonstrate that the proposed framework outperforms several existing active learning methods.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.002
Open science0.0030.002
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.330
Teacher spread0.296 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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