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Record W7126699968

Extra Adrenal Paraganglioma in a Mixed Breed Dog

2017· other· en· W7126699968 on OpenAlexaboutno aff
Michael Merkhassine

Bibliographic record

VenueeCommons (Cornell University) · 2017
Typeother
Languageen
Field
Topic
Canadian institutionsnot available
Fundersnot available
KeywordsParagangliomaCytologyLabrador RetrieverPresentation (obstetrics)ImmunohistochemistryChemotherapyNeuroendocrine tumorsWork-up
DOInot available

Abstract

fetched live from OpenAlex

A 12-year-old female spayed poodle mix presented to the Cornell University Hospital for Animals (CUHA) Internal Medicine service on referral for evaluation of chronic soft stool and pancreatitis. The work up revealed a mild thrombocytopenia, which progressed to moderate over the next two weeks, and a peri-aortic sublumbar mass. Based on these clinical abnormalities, an immune-mediated thrombocytopenia secondary to neoplasia was prioritized. A fine needle aspirate (FNA) of the mass with cytologic evaluation was planned but delayed pending improvement of the thrombocytopenia. Following successful medical management, the cytology of the FNA was consistent with a tumor neuroendocrine or endocrine origin. A computed tomography (CT) scan was performed for surgical planning and to check for metastasis. The mass was surgically removed and submitted for histopathology, which revealed a malignant neuroendocrine tumor. Upon further immunohistochemical staining, a diagnosis of extra-adrenal paraganglioma was made. The patient subsequently presented to the CUHA Oncology service and began metronomic chemotherapy with chlorambucil. This presentation will discuss the diagnosis, pathophysiology, and treatment of paraganglioma.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.000
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.215
Teacher spread0.176 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2017
Admission routes1
Has abstractyes

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