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Record W7128717047 · doi:10.5935/1518-0557.20250192

In Vitro Fertilization and Placenta Accreta (spectrum): A Systematic Review

2025· article· en· W7128717047 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueJBRA · 2025
Typearticle
Languageen
FieldMedicine
TopicMaternal and fetal healthcare
Canadian institutionsnot available
Fundersnot available
KeywordsPlacenta accretaIn vitro fertilisationAssisted reproductive technologyInfertilityReproductive technologyPregnancyEmbryo transferReproductive medicine

Abstract

fetched live from OpenAlex

In vitro fertilization (IVF) has transformed infertility treatment, providing options for individuals struggling to conceive naturally, with significant success rates, particularly in women under 35. However, IVF pregnancies are associated with potential obstetric complications, notably placenta accreta spectrum (PAS), which necessitates early diagnosis and a multidisciplinary approach to safeguard maternal-fetal health. This systematic review involved a comprehensive search of databases such as PubMed, Cochrane Library, BVS, Embase, Web of Science, and Scopus using specific terms related to IVF and PAS. Original studies comparing spontaneous pregnancies to IVF pregnancies were included, while case reports and non-peer-reviewed articles were excluded. Data extraction was standardized, and study quality was assessed using the Newcastle-Ottawa tool. The analysis covered thirteen articles involving 252,295 assisted reproductive technology pregnancies and over 16 million spontaneous pregnancies. A key finding is the increased risk of PAS in IVF pregnancies, with some studies indicating that frozen embryo transfer (FET) poses a higher risk than fresh embryo transfer. Additional complications include hypertension, preeclampsia, and intrauterine growth restriction (IUGR). Interestingly, some research suggests a lower Intensive Care Unit admission rate for women with placenta accreta after IVF compared to those with spontaneous conception. This indicates that while assisted reproductive technology is an independent risk factor for PAS, it presents a unique risk profile. The review emphasizes the need for further research into maternal outcomes related to PAS after assisted reproductive techniques (ART) and highlights the importance of specialized follow-up and rigorous prenatal diagnosis to minimize complications in these pregnancies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.478
Threshold uncertainty score0.167

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.317
Teacher spread0.308 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it