Prenatal Glycemic Control and Early Childhood Adiposity Among Offspring of Women with Type 2 Diabetes: A Cohort Study
Bibliographic record
Abstract
Objective: This thesis examined whether maternal glycemic control during pregnancy is predictive of offspring adiposity among pregnancies complicated by type 2 diabetes.Methods: 283 eligible mothers with type 2 diabetes who participated in a randomized controlled trial and its follow-up study were included in the study cohort. Maternal glycemic control by trimester and offspring adiposity measurements up to 24 months of age were prospectively collected. Results: Mean maternal capillary blood glucose (CBG) in second trimester had a weak positive association with offspring body mass index (BMI) z-score at 18 months of age, but not at 24 months. Second trimester hemoglobin A1c (HbA1c) and mean CBG predicted risk of childhood obesity at 24 months. Third trimester glycemic control had no impact on offspring adiposity in early childhood. Conclusion: A weak positive association was found between maternal glycemic control in the second trimester and offspring adiposity up to 24 months of age in pregnancies complicated by type 2 diabetes.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".