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Record W7132901529

CMOS biosensors

2007· dissertation· W7132901529 on OpenAlexaff
Cintia Man

Bibliographic record

VenueTSpace · 2007
Typedissertation
Language
FieldChemical Engineering
TopicAnalytical Chemistry and Sensors
Canadian institutionsUniversity of TorontoOntario College of Art and DesignLibrary and Archives Canada
Fundersnot available
KeywordsBiosensorPotentiometric titrationCMOSElectrodeDielectric spectroscopyChipTransistorElectrical impedance
DOInot available

Abstract

fetched live from OpenAlex

Two biosensor chips, realized in standard 0.18μm CMOS, are presented with test results using biological analytes. The electrochemical biosensor, consisting of a 3×3 array of three-electrode sensing elements, occupies 1.4mm2, and can be reconfigured dynamically, via on-chip register, to perform: impedance spectroscopy, amperometric and potentiometric analysis. The design follows concepts previously published, but uses new transistor sizing and placement. Impedance spectroscopy test results are presented for the protein linker BSA; previous work is extended by presenting test results for different size on-chip aluminum-alloy electrodes offering an effective approach to detect different concentrations. The second design, the SEPTIC Detector, detects ions that flood out from a targeted bacterial cell wall when specific bacteriophages are applied. The 1.1mm2 chip is the first to confirm the efficacy of CMOS and aluminum alloy electrodes spaced to create a 0.46μm×10μm×0.9μm trench. Test results confirm identification of E. coli W3110 bacteria cells using bacteriophage λ, within 160sec.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.021
Threshold uncertainty score0.070

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0030.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0210.022

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.349
Teacher spread0.330 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2007
Admission routes1
Has abstractyes

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