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Record W7132951657

Properties of Biopolymer Films in Ionic Solutions and their Applications as 3D Printed Personalized Wound Dressings

2019· dissertation· W7132951657 on OpenAlexfundno aff
Daniel Pinto Ramos

Bibliographic record

VenueTSpace · 2019
Typedissertation
Language
FieldMedicine
TopicWound Healing and Treatments
Canadian institutionsnot available
FundersUniversity of Toronto
KeywordsBiopolymerDissolutionIonic strengthIonic bondingRhodamine BCelluloseSwellingBiocompatibilityComposite numberBiomaterial
DOInot available

Abstract

fetched live from OpenAlex

This thesis describes the effects of ionic solutions on biopolymer films and the development of a 3D printed personalized wound dressing. Chitosan, gelatin, and composite chitosan/gelatin films were exposed to NaCl, Na2SO4, and CaCl2 solutions with varying ionic strength and their swelling and dissolution properties were measured. In addition, the release of the small ionic molecules Rhodamine B and Eosin Y from films into NaCl solutions of varying ionic strength was monitored. Next, a shear-thinning mixture of cellulose nanocrystals and chitosan-methacrylate was extruded with various patterns and polymerized by ultraviolet light irradiation or elevated temperature to form hydrogel wound dressings. Antimicrobial silver nanoparticles, a model protein (bovine serum albumin), and an antibiotic (gentamicin) were added to the hydrogel mixtures and their release from the dressings was monitored. In addition, phenol red-methacrylate was co-polymerized into the hydrogel dressing and exhibited a pH-responsive colour change suitable for the detection of infection.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.341
Teacher spread0.300 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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