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Record W7133022576

Developmental Effects of Concurrent Vestibular and Auditory Impairments in Childhood

2025· dissertation· W7133022576 on OpenAlexfundno aff
Melissa Hazen

Bibliographic record

VenueTSpace · 2025
Typedissertation
Language
FieldNeuroscience
TopicVestibular and auditory disorders
Canadian institutionsnot available
FundersArmy Research OfficeHospital for Sick ChildrenUniversity of Toronto
KeywordsVestibular systemCognitionHearing lossCochlear implantBalance (ability)Motor skillAudiometry
DOInot available

Abstract

fetched live from OpenAlex

This thesis aimed to examine how hearing loss, vestibular dysfunction, and socioeconomic factors influence the development of balance, spatial learning, and cognitive outcomes in children with cochlear implants. While children with hearing loss are known to experience delays in motor and cognitive domains, the extent to which these delays relate to underlying vestibular dysfunction, reduced auditory experience, or environmental factors remains unclear. It was hypothesized that poor balance and spatial difficulties would be more prevalent in children with cochlear implants, but that learning could occur with repeated exposure and experience.To explore this, three complementary studies were conducted. The first study analyzed clinical data from 334 children with and without hearing loss and found that balance problems were significantly more common in children with hearing loss, particularly when vestibulo-ocular reflex (VOR) function was impaired. These results support the importance of VOR assessments in identifying children at risk for motor delays. The second study evaluated language, working memory, and academic performance in 96 children, 66 with bilateral cochlear implants compared to 30 typically developing peers. Although all children improved with age, those with cochlear implants demonstrated persistent deficits across all domains. Analyses revealed that developmental outcomes were most strongly associated with duration and quality of auditory experience, rather than vestibular or socioeconomic factors alone. Children with specific etiologies such as congenital cytomegalovirus and structural inner ear anomalies were particularly affected. The final study assessed spatial learning in 54 children during a 5-day camp using novel, mobile tasks of balance, auditory localization, and visuospatial memory. Children with cochlear implants (n=21) performed more poorly than their peers (n=19) across all tasks but demonstrated learning over time in visuospatial and balance domains, suggesting that these abilities are malleable with experience. Auditory spatial performance was more limited but showed improvement in reaction time for children with greater auditory experience. Taken together, these findings highlight the complex interplay between sensory input, neural development, and experience. While delays are evident in children with cochlear implants, the capacity for improvement underscores the importance of early intervention, balance screening, and individualized supports that promote spatial and cognitive development in this high-risk population.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.024

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.290
Teacher spread0.282 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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