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Record W7133027800

Three Dimensional Musculoaponeurotic Architecture and Innervation of the Human Flexor Digitorum Superficialis and Flexor Digitorum Profundus: Functional Implications

2022· dissertation· W7133027800 on OpenAlexaboutno aff
Emma S. Campisi

Bibliographic record

VenueTSpace · 2022
Typedissertation
Language
FieldMedicine
TopicBotulinum Toxin and Related Neurological Disorders
Canadian institutionsnot available
Fundersnot available
KeywordsMuscle architectureBotulinum toxinSpasticityMuscle contractureStroke (engine)ContractureConnective tissueJoint Contracture
DOInot available

Abstract

fetched live from OpenAlex

Stroke is a leading cause of disability in Canada. Up to 80% of stroke survivors develop post stroke spasticity that results in pain, stiffness and joint contractures that negatively impacts quality of life. Botulinum toxin injection into the target muscle is essential for effective and safe treatment of muscle spasticity. Flexor digitorum superficialis (FDS) and flexor digitorum profundus (FDP) muscles are commonly affected, however, the recommended sites of injection vary. The aim was to construct a volumetric 3D model of the contractile and connective tissue elements of the digital bellies FDS and FDP to determine their functional characteristics and optimal botulinum toxin injection sites. The musculoaponeurotic architecture of FDS and FDP, and intramuscular innervation of FDP, were defined in 3D space. This thesis elucidates the morphology, relative functional capabilities, and optimal botulinum toxin injection sites of the digital bellies of FDS and FDP.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.307
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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