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Record W7133041997

Transition Metal Hydride Complexes: From Computation to Catalysis and Everything in Between

2022· dissertation· W7133041997 on OpenAlexaff
Tsz Ho Tsui

Bibliographic record

VenueTSpace · 2022
Typedissertation
Language
FieldChemistry
TopicAsymmetric Hydrogenation and Catalysis
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsHydrideMoietyCarbeneTransition metalCatalysisTransfer hydrogenationTransition stateRuthenium
DOInot available

Abstract

fetched live from OpenAlex

Computational methods were used to investigate transition metal hydride complexes both in the ground state and as reactive intermediates. Chapter 2 investigates an interesting phenomenon concerning the reversal of the relative position of the antisymmetric and symmetric vibrational modes of trans-dihydrides of transition metals and main group elements. These findings were used to show the different modes of hydride attack on CO2 by a transition metal and main group porphyrinate trans-dihydride complex. Chapter 3 details both an experimental and computational study on the catalytic transfer hydrogenation of aryl ketones with basic iso-propanol by a ruthenium hydride complex with a protic N-heterocyclic carbene ligand. The bifunctional character of the protic N-heterocyclic carbene moiety was determined to play a crucial role in the mechanism of the inner-sphere hydride transfer to acetophenone in a computational study. Chapter 4 describes the synthesis of an iridium(III) azolato complex through rearrangement of a tethered C8-iodinated theophylline fragment. The rearrangement proceeds through an unusual seven-coordinate cationic iridium(V) hydride intermediate which is supported by computational analysis. Finally, chapter 5 concerns the development of an undergraduate laboratory experiment in which an iron carbonyl complex is synthesized to investigate its catalytic activity in the transfer hydrogenation of acetophenone.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.325
Teacher spread0.306 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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