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Record W7133094623

Development and Validation of a Novel Multimodal Exertional Test for Concussion Assessment

2025· dissertation· W7133094623 on OpenAlexfundno aff
Kyla Lia Pyndiura

Bibliographic record

VenueTSpace · 2025
Typedissertation
Language
FieldMedicine
TopicTraumatic Brain Injury Research
Canadian institutionsnot available
FundersUniversity of TorontoU.S. Department of Veterans Affairs
KeywordsConcussionAthletesTest (biology)Reliability (semiconductor)Sports medicineBalance (ability)Competitive athletesCognitive test
DOInot available

Abstract

fetched live from OpenAlex

Concussion management is consistently evolving, with exertional testing playing an increasingly important role in return-to-sport decisions. The purpose of this thesis was to develop, evaluate, and implement a multimodal exertional test (MET) to support clinical decision making in concussion care. The first study focused on the development and pilot testing of a structured four-stage, twelve-task MET that progressively increased in complexity: Stage 1) introduced cardiovascular load, Stage 2) incorporated head acceleration, Stage 3) added cognitive tasks, and Stage 4) involved balance and multi-plane movements. Pilot testing with healthy athletes demonstrated that the MET elicited appropriate increases in heart rate, without provoking symptoms, suggesting the MET is both physiologically demanding and well-tolerated. The second study assessed the test-retest reliability of the MET in healthy athletes across two sessions. Results indicated good reliability across symptom reporting, physiological responses, and performance metrics. Improvements in certain task completion times were observed in the second session, likely reflecting learning effects. The third and final study examined the validity and prognostic ability of the MET by comparing performance between healthy athletes and athletes with concussion. Athletes with concussion reported greater symptom provocation and were more likely to fail in completing all tasks, whereas all healthy athletes completed the MET without symptom exacerbation. Additionally, based on MET performance during the first week of injury, athletes with concussion who successfully passed all twelve tasks had a shorter recovery length in comparison to athletes who failed. Altogether, these studies provided the foundational evidence supporting the MET as a reliable, valid, and feasible tool for clinical concussion assessment. The MET offers a structured and scalable approach to exertional testing and may aid in the readiness to return-to-sport, advancing best practices in concussion management.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.030

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.008
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.104
GPT teacher head0.457
Teacher spread0.352 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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