MétaCan
Menu
← Back to cohort
Record W7133095088

Predictors of cardiovascular events and death in paediatric renal transplant recipients

2008· dissertation· W7133095088 on OpenAlexfundno aff
Susan M. Koshy

Bibliographic record

VenueTSpace · 2008
Typedissertation
Language
FieldMedicine
TopicRenal Transplantation Outcomes and Treatments
Canadian institutionsnot available
FundersHospital for Sick ChildrenInstitute for Clinical Evaluative SciencesAstraZeneca
KeywordsDialysisRetrospective cohort studyDiseaseDiabetes mellitusTransplantationCohortRenal functionCause of death
DOInot available

Abstract

fetched live from OpenAlex

Cardiovascular (CV) disease is the leading cause of death in pediatric renal transplant patients (pRTx). We examined the roles of hypertension, donor type, estimated glomerular filtration rate (eGFR), pre-transplant dialysis and post transplant diabetes (PTDM) on fatal and non-fatal CV events and all-cause mortality in pRTx. The study design is a population-based retrospective cohort study of 226 children with end-stage renal disease who received 1st renal transplants during 1980--2000 using record linkage between medical charts and administrative health databases. Primary outcomes were time to death and first fatal or non-fatal CV events. 71% of all CV events were non-fatal events. Pre-emptive transplantation was associated with decreased hazard of CV events (HR 0.30, 95% CI 0.09-0.99, p = 0.05). eGFR

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.296
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2008
Admission routes1
Has abstractyes

Explore more

Same venueTSpace→Same topicRenal Transplantation Outcomes and Treatments→French-language works237,207→