PILI ON MENINGOCOCCI FROM PRIMARY CULTURES OF NASOPHARYNGEAL CARRIERS AND CEREBROSPINAL FLUID OF PATIENTS WITH ACUTE DISEASE*
Bibliographic record
Abstract
Although pili have been observed on the surfaces of several strains of Neisseria meningitidis (2, 4), the proportion of cells in a population that possess these structures is generally less than 5 %. Furthermore, these few piliated cells seldom exhibit more than one or two pill per cell (2). One exceptional strain of meningococcus (ATCC 13090), however, routinely produces abundant pili on nearly all the cells of the population (> 80%) under a variety of laboratory growth conditions (2). In the close relative, Neisseria gonorrhoeae, Kellogg et al. (5, 6) found a correlation between colony type and virulence. Swanson et al. (10) and Jephcott et al. (4) reported that only cells from the virulent colony types were piliated suggesting that pili may be linked to the property of virulence in the gonococcus. Furthermore, the piliated gonococci were found to have a greater ability to adhere to both tissue culture cells (9) and sperm cell surfaces (3), both of which could give these cells a selective advantage in the urinary tract. Other data suggest that pili may also aid this bacterium in resisting phagocytosis (7). The work presented here is the result of a field survey of meningococci from known carriers at the Canadian Forces Base, Cornwallis, Nova Scotia and also from patients with acute meningococcal disease in Sao Paulo, Brazil.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".