Peplomer bulb shape and coronavirus rotational diffusivity
Bibliographic record
Abstract
Recently, the rotational diffusivity of the coronavirus particle in suspension was calculated, from first principles, using general rigid bead-rod theory [M. A. Kanso, Phys. Fluids 32, 113101 (2020)]. We did so by beading the capsid and then also by replacing each of its bulbous spikes with a single bead. However, each coronavirus spike is a glycoprotein trimer, and each spike bulb is triangular. In this work, we replace each bulbous coronavirus spike with a bead triplet, where each bead of the triplet is charged identically. This paper, thus, explores the role of bulb triangularity on the rotational diffusivity, an effect not previously considered. We thus use energy minimization for the spreading of triangular bulbs over the spherical capsid. The latter both translates and twists the coronavirus spikes relative to one another, and we then next arrive at the rotational diffusivity of the coronavirus particle in suspension, from first principles. We learn that the triangularity of the coronavirus spike bulb decreases its rotational diffusivity. For a typical peplomer population of 74, bulb triangularity decreases the rotational diffusivity by 39%.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".