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Record W7160392509 · doi:10.5061/dryad.pvmcvdp0s

Compilation of human secretome-encoding genes, their phylogenetic age, and some of their expression properties.

2025· dataset· en· W7160392509 on OpenAlexaff
Jose Ranz, Alberto Civetta

Bibliographic record

VenueOpen MIND · 2025
Typedataset
Languageen
Field
Topic
Canadian institutionsUniversity of Winnipeg
Fundersnot available
KeywordsPhylogenetic treeGeneVertebratePhylogeneticsExpression (computer science)

Abstract

fetched live from OpenAlex

This dataset is a compilation of human secretome-encoding genes, their phylogenetic age, and some of their expression properties. This information was used to determine whether all secretome-by-evolutionary-transition combinations experienced similar gains of new genes during vertebrate evolution. We found that the male reproductive secretome experienced the largest addition of new genes during the eutherian radiation compared to any other secretome-by-evolutionary-transition combination. Most of these new genes are preferentially expressed in the epididymis, pointing to this organ as the one that underwent the largest reconfiguration among those in the male reproductive tract. These data can be used with no restrictions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Dataset · Consensus signal: Dataset
Teacher disagreement score0.033
Threshold uncertainty score0.109

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0020.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0040.006
Science and technology studies0.0010.000
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0330.032

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.079
GPT teacher head0.319
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreDataset

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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