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A Machine Learning-based Dynamic SST Index for Long-lead Malaria Prediction in the Peruvian Amazon

2025· article· W7161035996 on OpenAlexaff
Mengxin Pan, Shineng Hu, Mark Janko, Benjamin F Zaitchik, Ken Takahashi, Andres G Lescano, César V. Munayco, Wei Pan

Bibliographic record

Venuenot available
Typearticle
Language
FieldMedicine
TopicMalaria Research and Control
Canadian institutionsSimon Fraser University
Fundersnot available
KeywordsPredictabilitySea surface temperatureMalariaAmazon rainforestEl Niño Southern OscillationTropical climateGeneralized additive modelTropical AtlanticIndex (typography)

Abstract

fetched live from OpenAlex

Malaria imposes a major health burden in the Peruvian Amazon, and its early warning is essential for effective disease prevention. The tropical sea surface temperature (SST) variability, fundamentally shaping the global weather patterns, may also alter malaria transmission and potentially improve its long-lead predictability. In this study, we propose a machine learning-based methodology to identify long-lead predictors for Peruvian malaria from the ocean. First, we demonstrate that significant correlations broadly exist between tropical sea surface temperature (SST) anomalies and Peruvian malaria incidence across different seasons and time lags, confirming the potential predictability from the tropical ocean. Then, we apply the self-organizing map to synthesize the spatiotemporally varying SST-malaria relationship and identify a unique dynamic SST index for Peruvian malaria. The dynamic SST index provides better prediction performance (higher correlation coefficients and lower root mean square errors) in the single-predictor generalized linear model, compared to the traditional El Niño–Southern Oscillation (ENSO) index, with lead times exceeding three months. Furthermore, the dynamic SST index captures the evolution of the ENSO life cycle from its precursor climate mode (Pacific meridional mode) and appears to influence Peruvian malaria by altering the local near-surface air temperature and specific humidity. Such underlying mechanisms provide the physically plausible basis for the long-lead predictability of Peruvian malaria using a machine learning-based remote predictor.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.020

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.286
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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