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Record W7161994771 · doi:10.82308/27260

Hypertension and the risk of cancer : a population study

2001· dissertation· en· W7161994771 on OpenAlexaboutno aff
Themistocles L. Assimes

Bibliographic record

Venuenot available
Typedissertation
Languageen
FieldMedicine
TopicBlood Pressure and Hypertension Studies
Canadian institutionsnot available
Fundersnot available
KeywordsConfoundingCancerCausality (physics)Incidence (geometry)EpidemiologyCohort studyCancer incidencePopulation

Abstract

fetched live from OpenAlex

Several epidemiological studies have evaluated whether an association exists between hypertension and cancer with inconclusive results because of several design biases. Using the Saskatchewan Health Databases, a cohort of subjects with incident treated hypertension between 1980 and 1987 was assembled and followed until 1996 to identify all incident cancer hospitalizations. Age and sex-standardized incidence ratios for all cause and for site-specific cancers were estimated using provincial cancer rates. A small increased risk of all-cause cancer was found mainly among females (RR: 1.12, 95 percent CI 1.06--1.17). Site-specific analyses revealed increased risks for uterine, breast, bladder, kidney, and several less common cancers. Re-analyses to control for reverse causality and detection bias did not alter the findings. While this study suggests a weak association between hypertension and cancer, the inability to control for information bias and for certain confounders does not allow for a definitive conclusion on causality.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.037
Threshold uncertainty score0.073

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.004
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.310
Teacher spread0.286 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2001
Admission routes1
Has abstractyes

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