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Record W7162014158 · doi:10.82308/7986

Susceptibility to tetanus and diphtheria in recently arrived adult immigrants and refugees to Montreal, Quebec

2010· dissertation· en· W7162014158 on OpenAlexaboutno aff
Penny Gingrich

Bibliographic record

Venuenot available
Typedissertation
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicDiphtheria, Corynebacterium, and Tetanus
Canadian institutionsnot available
Fundersnot available
KeywordsDiphtheriaTetanusSeroprevalenceVaccinationImmunityImmigrationEpidemiology

Abstract

fetched live from OpenAlex

Background: Adult immigrants may have been under-immunized in their countries of origin. We estimated the seroprevalence and examined risk factors for susceptibility to diphtheria and tetanus. Methods: 1480 newly-arrived adult immigrants were recruited in Montreal, 2002-2004. We collected socio-demographic information and vaccination history, and measured serum antibodies to tetanus and diphtheria by EIA to identify susceptibility, defined as ≤0.15 IU/ml and ≤0.10 IU/ml, respectively. Results: 45% (95% CI, 42%-48%) of immigrants, mean age 31 +/- 8.6 years, lacked immunity to either tetanus or diphtheria, ranging by region of origin (23%-79%). 32% (95% CI, 30%-34%) were susceptible to tetanus and susceptibility increased with age. Susceptibility to diphtheria was less prevalent [26% (95% CI, 24%-28%)] and decreased with age. Conclusions: Many adult immigrants would benefit from diphtheria/tetanus vaccine. Susceptibility to tetanus suggests under-vaccination, while decreasing susceptibility to diphtheria with age suggests that immunity has been boosted from ongoing transmission in some countries of origin.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.786
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.246
Teacher spread0.242 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2010
Admission routes1
Has abstractyes

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