Treatment of Vascular Cognitive Impairment by “Huayu Tongluo” Moxibustion
Bibliographic record
Abstract
Objective To observe the therapeutic effect of"Huayu Tongluo"(blood stasis-removing and meridian-collateraldredging)moxibustion for vascular cognitive impairment(VCI)patients and changes of insulin like growth factor-1(IGF-1)levels in serum after the treatment.Methods Sixty patients with VCI were randomly divided into medication(control)and moxibustion groups(n=30 in each group).Cotton cloth-separated moxibustion was applied to Baihui(GV 20)and Shenting(GV 24),and conventional moxibustion applied to Dazhui(GV 14)and Yongquan(KI 1)for 30 min,once daily,6 times a week and for 30 days.Patients of the control group were treated by oral administration of Donepezil hydrochloride at the dose of 5 mg/night for 30 days.The core symptoms of traditional Chinese medicine(TCM),mini-mental state examination(MMSE),activity of daily living(ADL)and Montreal cognitive assessment(MoCA)scales were used to assess the therapeutic effect after the treatment.The content of serum IGF-1 was determined by ELISA.Results Of the two 30 cases in the control and moxibustion groups,9 and 17 experienced marked improvement,13 and were effective,8 and 3 ineffective,with the effective rates being 73.33% and90.00%,respectively.The effective rate in the moxibustion group was obviously higher than that in the control group(P<0.05).After the treatment,the TCM symptom scores were significantly decreased,and the MMSE,ADL and MoCA scores considerably increased in both groups compared with those of their own individual pre-treatment(P<0.01).The TCM symptom score of the moxibustion group was significantly lower,and the MMSE and ADL scores were obviously higher than those of the control group(P<0.01).The serum IGF-1 content in both groups was significantly increased after the treatment relevant to that of their own individual pre-treatment(P<0.01),and was obviously higher in the moxibustion group than in the control group(P<0.01).No significant difference was found between the two groups in the MoCA score after the treatment(P>0.05).Conclusion "Huayu Tongluo"moxibustion has a positive effect for patients with VCI,which may be associated with its effect in up-regulating serum IGF-1 level.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".