Treatment of Knee Osteoarthritis with Acupuncture plus Intra-articular Injection of Sodium Hyaluronate
Bibliographic record
Abstract
Objective To examine the clinical benefits of acupuncture combined with intra-articular injection of sodium hyaluronate for knee osteoarthritis(KOA)patients.Methods A total of 150 KOA patients were randomized into simple medication and acupuncture plus medication(combined treatment)groups(n=75 in each).For all the patients,intra-articular injection of sodium hyaluronate(2 mL)was performed once a week for 5 weeks,and for patients of the combined treatment group,filiform needles were separately inserted into unilateral or bilateral Zusanli(ST 36),Liangqiu(ST 34),Yanglingquan(GB 34),Yinlingquan(SP 9),Xiyangguan(GB 33),Dubi(ST 35),Neixiyan(EX-LE 4)and Xuehai(SP 10)according to the focus,and manipulated with the uniform reinforcing and reducing technique,followed by retaining the needles for 30 min.The acupuncture treatment was given once every day or every other day,5 weeks in total.The visual analog scale(VAS)was used to assess the pain severity of kneejoint,and the Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC)employed to assess the 1)pain severity during various positions or movements(20 points),2)severity of joint stiffness(8 points),and 3)difficulty in performing daily functional activities(68 points).The therapeutic effect was evaluated according to the decreased level of WOMAC subscale scores and improvement of daily activities.Results After the treatment,the VAS scores of both medication and combined treatment groups were decreased significantly in comparison with their own pre-treatment in each group(P<0.05),and that of the combined treatment group was significantly lower than that of the medication group(P<0.05).WOMAC and daily activity findings showed that of the two 75 KOA patients in the medication and combined treatment groups,16(21.33%)and 32(42.67%)experienced marked improvement,46(61.33%)and 38(50.67%)were improved,and 13(17.33%)and 5(6.67%)ineffective,with the total effective rates being 82.67% and 93.33%,respectively.The therapeutic effect of the combined treatment group was apparently superior to that of the simple medication group(P<0.05).Conclusion Acupuncture combined with intraarticular injection of sodium hyaluronate is effective in improving KOA patients' pain severity and other symptoms as well as functional activities.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".