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Record W777635729

Competitive interference between influenza viral strains

2011· article· en· W777635729 on OpenAlexvenueno aff
Seyed M. Moghadas, Christopher S Bowman, Julien Arino

Bibliographic record

VenueNPARC · 2011
Typearticle
Languageen
FieldMathematics
TopicCOVID-19 epidemiological studies
Canadian institutionsnot available
Fundersnot available
KeywordsVirologyViral InterferenceInterference (communication)BiologyVirusComputer scienceViral replicationTelecommunications
DOInot available

Abstract

fetched live from OpenAlex

ABSTRACT. We propose a modelling framework for inves-tigating the dynamics of competition between immunologically-related in\nuenza viral strains in the absence of pre-existing im-munity. Assuming that the host immune system will mount partial protection (cross-immunity) against one strain by virtue of having interacted with the other through exposure, we dis-cuss the conditions for the occurrence of two distinct waves of infection during a single epidemic episode. Numerical sim-ulations are presented to illustrate the possibility of infection waves with respect to the protection level induced by the rst strain, and the time-lag for evolving the second strain. We pro-pose directions for future work that involves extension of the model to include vaccination. 1 Introduction An important feature of in\nuenza virus replica-tion is the high mutation rates exhibited over short time scales [7, 11].

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.380
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.419
GPT teacher head0.426
Teacher spread0.007 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2011
Admission routes1
Has abstractyes

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