Asthma in apprentice workers The birth cohort parallel: Using apprentices as a powerful cohort design for studying occupational asthma
Bibliographic record
Abstract
This chapter presents a review of longitudinal studies of apprentices in trades and professions entailing substantial risks for the development of occupational asthma (OA). Prospective studies of OA enable the assessment of host characteristics before apprentices/workers enter a particular workforce, thus before being exposed to a suspected etiological agent, as well as the early detection of sensitization to a specific work-related antigen and the evaluation of bronchial responsiveness before onset of symptoms of asthma. Since 1973, several cohort studies have been conducted in Europe and Canada among apprentices exposed to high- and low-molecular-weight agents. The investigated outcomes were, apart from OA, work-aggravated asthma, bronchial hyperresponsiveness, work-related symptoms and specific sensitization. The rate of onset of the relevant outcomes was high even after 1 year of training; the implications for setting timing of surveillance programs would be to screen for sensitization and symptoms in the first 2–3 years of apprenticeship. Several host factors assessed at baseline were identified as risk factors for the incidence of work-related outcomes. However, more investigations are needed to explore the extent to which the risk of work-related allergy and asthma increases with exposure characteristics during apprenticeship. Directions for research in the existing cohorts and in future ones are suggested.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".