Identification of plasmids in a Salmonella Typhimurium septicemic isolate without the classical 95 kb virulence plasmid
Bibliographic record
Abstract
In this study, we report the characterization of plasmids from a Salmonella Typhimurium strain isolated from a septicemic pig.This isolate did not possess the classical 95 kb plasmid associated with virulence, but contained several low molecular weight plasmids.This isolate was as well one of the most invasive in intestinal epithelial cell lines (58.34 ± 7.32%) and showed no acquire resistance to tested antimicrobial agents.We therefore sequenced these plasmids.The size of the first plasmid, pST36-4-b5, was 3.6 kb and the size of pST36-1-b6, the second one, was 4.9 kb.They contained some open reading frames (ORF) that carry some genetic information for replication and mobilization.These plasmids contained also information for enzymatic functions and some hypothetical proteins also found in various bacterial species.Finally, a third plasmid has been partially characterized.The size of this plasmid is higher than the two other plasmids.These plasmids contained several genes of unknown function that will need to be further studied for their putative role in virulence.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".