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Reaction time performance is related to brain blood flow during gravitational stress

2012· article· en· W81102895 on OpenAlexafffundabout
Aaron A. Phillips, Darren E. R. Warburton, C. Taylor Drury, Shannon S. D. Bredin

Bibliographic record

VenueThe FASEB Journal · 2012
Typearticle
Languageen
FieldMedicine
TopicHeart Rate Variability and Autonomic Control
Canadian institutionsUniversity of British Columbia
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsCerebral blood flowMedicineHeart rateBlood pressureBlood flowCardiologyAnesthesiaInternal medicine

Abstract

fetched live from OpenAlex

Speed of information processing is critical to effective air combat; however, little is known about the effect of gravitational stress on measures of processing speed. To examine, eight young healthy males (26 ± 6 years of age) underwent progressive lower body negative pressure (LBNP) while recording beat‐to‐beat blood pressure (BP), heart rate variability, brain blood flow (MCABF), and while testing simple reaction time (SRT). Baseline values were compared to the last tolerated stage of LBNP (LBNPmax) and the median stage (LBNP50). During LBNP, SRT was significantly slower compared to baseline (Baseline: 280±33, LBNP50: 324±39, LBNPmax: 316±37 ms, P < 0.05). Also, MCABF (Baseline: 65±6, LBNP50: 63±63, LBNPmax: 59±60 cm/s, P < 0.05) and pulsatility index (Baseline: 0.83±0.1, LBNP50: 0.72±0.15, LBNPmax: 0.65±0.1 au, P < 0.05) decreased during LBNPmax. From baseline to LBNP50 a significant correlation existed between changes in pulsatility index and SRT (r = −0.7; P < 0.05). Our data shows that SRT increases during LBNP. Further, it appears that at moderate gravitational stress those with greater reductions in brain blood perfusion demonstrate a more profound negative affect on SRT. At severe LBNP however, SRT does not appear to be related to brain blood flow or indirect markers of sympathovagal tone. This research was supported by the Natural Sciences and Engineering Research Council of Canada.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.240
Teacher spread0.231 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2012
Admission routes3
Has abstractyes

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