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Record W958918613

外周血CD4~+CD25~+ Treg细胞与HBV携带者相关性的Meta分析

2013· article· zh· W958918613 on OpenAlexaboutno aff
潘宗琴, 吕红, 胡世芸, 陈宇, 庄勤建, 徐林, 姚新生, 肖政, 邱隆敏

Bibliographic record

Venue世界华人消化杂志 · 2013
Typearticle
Languagezh
FieldMedicine
TopicHepatitis B Virus Studies
Canadian institutionsnot available
Fundersnot available
KeywordsHepatitis B virusMedicineHBsAgVirologyImmunologyTreg cellIL-2 receptorVirusImmune systemT cell
DOInot available

Abstract

fetched live from OpenAlex

目的: 探讨CD4^+CD25^+Treg细胞在乙型肝炎病毒(hepatitis B virus, HBV)携带者及相关感染状态中分布特征, 以期揭示其与HBV携带者的相关性, 为临床干预提供依据. 方法: 计算机检索Pubmed、SCI、Embase、CNKI、万方及维普等数据库, 依据Newcastle-Ottawa Scale(NOS)标准评价文献质量, 按照PICOS原则提取资料, 采用RevMan5.1软件进行Meta分析. 结果: 纳入文献24篇. HBV携带者外周血Treg细胞含量较健康对照高(P = 0.01); 与HBV携带者比较, 慢性乙型肝炎Treg细胞含量较高(P = 0.12), 急性乙型肝炎较低(P = 0.15); 慢性HBV携带者Treg细胞高于非活动性HBsAg携带者(P = 0.01). Treg细胞含量与HBV DNA、丙氨酸转氨酶是否存在相关性, 因研究一致性差, 结论尚不能确定. 结论: CD4^+CD25^+Treg细胞可能成为影响HBV携带者预后及转归的重要因素.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.015
metaresearch head score (Gemma)0.030
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (broad)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.997
Threshold uncertainty score0.080

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0150.030
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.009
Bibliometrics0.0030.002
Science and technology studies0.0010.001
Scholarly communication0.0030.003
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.284
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designMeta-analysis
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2013
Admission routes1
Has abstractyes

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