All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins
2014· article· en· Nature Methods· Neuroscience
afffundno abstract
825
citations
Works
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Pluripotent stem cells in disease modelling and drug discovery
2016· review· en· Nature Reviews Molecular Cell Biology· Biochemistry, Genetics and Molecular Biology
fundno affno abstract
596
citations
A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ
2019· article· en· Neuron· Medicine
fundno affno abstract
332
citations
Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells
2017· article· en· Nature· Biochemistry, Genetics and Molecular Biology
affno abstract
297
citations
Corticoamygdala Transfer of Socially Derived Information Gates Observational Learning
2018· article· en· Cell· Neuroscience
fundno affno abstract
293
citations
282
citations
Homeostatic Epidermal Stem Cell Self-Renewal Is Driven by Local Differentiation
2018· article· en· Cell stem cell· Biochemistry, Genetics and Molecular Biology
fundno affno abstract
218
citations
Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation
2021· article· en· Science Immunology· Immunology and Microbiology
aff
175
citations
Sodium Channel SCN3A (NaV1.3) Regulation of Human Cerebral Cortical Folding and Oral Motor Development
2018· article· en· Neuron· Biochemistry, Genetics and Molecular Biology
affno abstract
167
citations
A psychiatric disease-related circular RNA controls synaptic gene expression and cognition
2020· article· en· Molecular Psychiatry· Biochemistry, Genetics and Molecular Biology
aff
167
citations
Functional and topological diversity of LOV domain photoreceptors
2016· article· en· Proceedings of the National Academy of Sciences· Agricultural and Biological Sciences
afffund
165
citations
Self-Condensation Culture Enables Vascularization of Tissue Fragments for Efficient Therapeutic Transplantation
2018· article· en· Cell Reports· Medicine
aff
140
citations
Neuronal interleukin-1 receptors mediate pain in chronic inflammatory diseases
2020· article· en· The Journal of Experimental Medicine· Medicine
afffund
127
citations
REST suppression mediates neural conversion of adult human fibroblasts via microRNA‐dependent and ‐independent pathways
2017· article· en· EMBO Molecular Medicine· Biochemistry, Genetics and Molecular Biology
fundno aff
113
citations
Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis
2019· article· en· Nature Medicine· Biochemistry, Genetics and Molecular Biology
aff
112
citations
Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation
2019· article· en· Cell stem cell· Medicine
affno abstract
108
citations
The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles
2018· article· en· Cell Reports· Biochemistry, Genetics and Molecular Biology
fundno aff
107
citations
Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data
2017· article· en· Nature Communications· Computer Science
aff
100
citations
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS
2023· article· de· Cell· Medicine
affno abstract
98
citations
Dynactin1 depletion leads to neuromuscular synapse instability and functional abnormalities
2019· article· en· Molecular Neurodegeneration· Medicine
fundno aff
92
citations
Adult axolotls can regenerate original neuronal diversity in response to brain injury
2016· article· en· eLife· Neuroscience
fundno aff
91
citations
Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer
2024· article· en· Cancer Cell· Biochemistry, Genetics and Molecular Biology
fundno aff
89
citations
Mapping of neuronal and glial primary cilia contactome and connectome in the human cerebral cortex
2023· article· en· Neuron· Biochemistry, Genetics and Molecular Biology
affno abstract
88
citations
Gradual differentiation uncoupled from cell cycle exit generates heterogeneity in the epidermal stem cell layer
2022· article· en· Nature Cell Biology· Biochemistry, Genetics and Molecular Biology
afffund
84
citations
Tumour budding is associated with the mesenchymal colon cancer subtype and RAS/RAF mutations: a study of 1320 colorectal cancers with Consensus Molecular Subgroup (CMS) data
2018· article· en· British Journal of Cancer· Medicine
fundno aff
81
citations