Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Full frame distilled prediction
Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
- Candidate categories
- Insufficient payload (model declined to judge)
- Consensus categories
- none
- Domain
- Candidate signal: noneConsensus signal: none
- Study design
- Candidate signal: Bench or experimentalConsensus signal: Bench or experimental
- Genre
- Candidate signal: EmpiricalConsensus signal: Empirical
- Teacher disagreement score
- 0.064
- Threshold uncertainty score
- 1.000
- Validation status
machine_predicted_unvalidated·codex-gemma-dda1882f352a
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
- Teacher spread
- 0.216 · how far apart the two teachers sit on this one work
- Validation status
score_only:v0-immature-baseline· verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it
Abstract
in nasal polyps and skin. These results indicate that MCs display distinct inflammation-associated effector programs and suggest that in situ MC proliferation is a major component of MC hyperplasia in human T2 inflammation.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
The record
- Venue
- Science Immunology
- Topic
- Mast cells and histamine
- Field
- Immunology and Microbiology
- Canadian institutions
- Artificial Intelligence in Medicine (Canada)
- Funders
- National Institute of General Medical SciencesNational Heart, Lung, and Blood InstituteHarvard Digestive Diseases Center, Harvard UniversityHorizon 2020 Framework ProgrammeAGA Research FoundationNational Institutes of HealthNational Institute of Allergy and Infectious DiseasesHoward Hughes Medical InstituteRichard and Susan Smith Family FoundationDirectorate-General for Research and InnovationSearle Scholars ProgramDamon Runyon Cancer Research FoundationAlfred P. Sloan FoundationEuropean CommissionNational Institute of Diabetes and Digestive and Kidney DiseasesBill and Melinda Gates FoundationNew York Stem Cell FoundationFood Allergy Science Initiative
- Keywords
- InflammationPhenotypeImmunologyBiologyMast cellAllergic inflammationMast (botany)Cell biologyGeneticsGene
- Has abstract in OpenAlex
- yes