Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
2007· article· en· Nature Genetics· Biochemistry, Genetics and Molecular Biology
affno abstract
1,751
citations
Works
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DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
2015· article· en· Cell· Biochemistry, Genetics and Molecular Biology
affno abstract
1,524
citations
FTO Obesity Variant Circuitry and Adipocyte Browning in Humans
2015· article· en· New England Journal of Medicine· Biochemistry, Genetics and Molecular Biology
afffund
1,396
citations
Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation
2000· article· en· Nature· Biochemistry, Genetics and Molecular Biology
affno abstract
1,387
citations
N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells
2014· article· en· Nature Cell Biology· Biochemistry, Genetics and Molecular Biology
affno abstract
1,329
citations
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
2010· article· en· Nature· Biochemistry, Genetics and Molecular Biology
affno abstract
1,190
citations
Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways
2008· article· en· Proceedings of the National Academy of Sciences· Medicine
aff
985
citations
Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission
2009· article· en· Journal of Biological Chemistry· Medicine
aff
955
citations
Activating mutations in ALK provide a therapeutic target in neuroblastoma
2008· article· en· Nature· Medicine
affno abstract
892
citations
The energy sensing LKB1–AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis
2007· article· en· Nature Cell Biology· Medicine
affno abstract
851
citations
A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria
2016· article· en· Cell· Biochemistry, Genetics and Molecular Biology
affno abstract
786
citations
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates
2021· article· en· Nature· Biochemistry, Genetics and Molecular Biology
affno abstract
768
citations
Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer
2012· article· en· Cell· Biochemistry, Genetics and Molecular Biology
fundno affno abstract
744
citations
Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy
2015· article· en· Nature Communications· Biochemistry, Genetics and Molecular Biology
aff
711
citations
Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells
2005· article· en· PLoS Biology· Medicine
affCorrection · OpenAlex missed it
708
citations
Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia
2011· article· en· Cancer Cell· Biochemistry, Genetics and Molecular Biology
afffundno abstract
694
citations
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration
2011· article· en· Nature· Biochemistry, Genetics and Molecular Biology
affno abstract
614
citations
The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice
2020· article· en· Nature Communications· Biochemistry, Genetics and Molecular Biology
fundno aff
574
citations
Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss
2015· article· en· Genes & Development· Biochemistry, Genetics and Molecular Biology
fundno aff
570
citations
The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing
2006· article· en· Nature Cell Biology· Biochemistry, Genetics and Molecular Biology
affno abstract
565
citations
Targeting circular RNAs as a therapeutic approach: current strategies and challenges
2021· review· en· Signal Transduction and Targeted Therapy· Biochemistry, Genetics and Molecular Biology
afffund
561
citations
Molecular biology of insect sodium channels and pyrethroid resistance
2014· article· en· Insect Biochemistry and Molecular Biology· Agricultural and Biological Sciences
affno abstract
560
citations
Hydrogen Sulfide Protects Against Cellular Senescence via S -Sulfhydration of Keap1 and Activation of Nrf2
2012· article· en· Antioxidants and Redox Signaling· Biochemistry, Genetics and Molecular Biology
afffund
558
citations
Asparagine bioavailability governs metastasis in a model of breast cancer
2018· article· en· Nature· Biochemistry, Genetics and Molecular Biology
affno abstract
554
citations
Requirement of DDX3 DEAD Box RNA Helicase for HIV-1 Rev-RRE Export Function
2004· article· en· Cell· Biochemistry, Genetics and Molecular Biology
affno abstract
553
citations