High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities
2015· article· en· Cell· Biochemistry, Genetics and Molecular Biology
afffundno abstract
1,790
citations
Works
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316 workspage 1 of 13
Epigenetics and the Biological Definition of Gene × Environment Interactions
2010· review· en· Child Development· Medicine
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1,218
citations
The fitness costs of antibiotic resistance mutations
2014· review· en· Evolutionary Applications· Biochemistry, Genetics and Molecular Biology
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722
citations
PERSPECTIVE: PURGING THE GENETIC LOAD: A REVIEW OF THE EXPERIMENTAL EVIDENCE
2002· review· en· Evolution· Biochemistry, Genetics and Molecular Biology
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515
citations
The genetical theory of kin selection
2011· article· en· Journal of Evolutionary Biology· Social Sciences
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442
citations
FIXATION OF NEW ALLELES AND THE EXTINCTION OF SMALL POPULATIONS: DRIFT LOAD, BENEFICIAL ALLELES, AND SEXUAL SELECTION
2000· review· en· Evolution· Biochemistry, Genetics and Molecular Biology
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399
citations
Quantitative analysis of fitness and genetic interactions in yeast on a genome scale
2010· article· en· Nature Methods· Biochemistry, Genetics and Molecular Biology
afffundno abstract
394
citations
Evolution of antifungal-drug resistance: mechanisms and pathogen fitness
2005· review· en· Nature Reviews Microbiology· Agricultural and Biological Sciences
afffundno abstract
367
citations
Evolutionary rescue and the limits of adaptation
2012· review· en· Philosophical Transactions of the Royal Society B Biological Sciences· Biochemistry, Genetics and Molecular Biology
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335
citations
Stress response during development predicts fitness in a wild, long lived vertebrate
2007· article· en· Proceedings of the National Academy of Sciences· Agricultural and Biological Sciences
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332
citations
The relationship between fitness and baseline glucocorticoids in a passerine bird
2008· article· en· General and Comparative Endocrinology· Agricultural and Biological Sciences
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305
citations
THE ECOLOGY AND GENETICS OF FITNESS IN CHLAMYDOMONAS. XII. REPEATED SEXUAL EPISODES INCREASE RATES OF ADAPTATION TO NOVEL ENVIRONMENTS
2002· article· en· Evolution· Biochemistry, Genetics and Molecular Biology
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289
citations
Body mass and individual fitness in female ungulates: bigger is not always better
2000· article· en· Proceedings of the Royal Society B Biological Sciences· Environmental Science
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281
citations
Distribution of fitness effects among beneficial mutations before selection in experimental populations of bacteria
2006· article· en· Nature Genetics· Biochemistry, Genetics and Molecular Biology
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275
citations
Intralocus Sexual Conflict Diminishes the Benefits of Sexual Selection
2006· article· en· PLoS Biology· Agricultural and Biological Sciences
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254
citations
Modelling the adaptive dynamics of traits involved in inter‐ and intraspecific interactions: An assessment of three methods
2001· article· en· Ecology Letters· Biochemistry, Genetics and Molecular Biology
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242
citations
Synergy of multiple partners, including freeloaders, increases host fitness in a multispecies mutualism
2010· article· en· Proceedings of the National Academy of Sciences· Agricultural and Biological Sciences
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237
citations
On the evolutionary origin of aging
2007· article· en· Aging Cell· Biochemistry, Genetics and Molecular Biology
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234
citations
Environmental duress and epistasis: how does stress affect the strength of selection on new mutations?
2010· review· en· Trends in Ecology & Evolution· Biochemistry, Genetics and Molecular Biology
affno abstract
209
citations
Genetic variance in fitness indicates rapid contemporary adaptive evolution in wild animals
2022· article· en· Science· Agricultural and Biological Sciences
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206
citations
An Evolutionary Cost of Separate Genders Revealed by Male‐Limited Evolution
2006· article· en· The American Naturalist· Agricultural and Biological Sciences
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198
citations
Linking genotypes to phenotypes and fitness: how mechanistic biology can inform molecular ecology
2009· review· en· Molecular Ecology· Biochemistry, Genetics and Molecular Biology
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196
citations
Old wine in new bottles: reaction norms in salmonid fishes
2011· review· en· Heredity· Agricultural and Biological Sciences
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191
citations
PARASITE TRANSMISSION MODES AND THE EVOLUTION OF VIRULENCE
2001· article· en· Evolution· Biochemistry, Genetics and Molecular Biology
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185
citations
What Do We Really Know About Adaptation at Range Edges?
2020· article· en· Annual Review of Ecology Evolution and Systematics· Biochemistry, Genetics and Molecular Biology
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184
citations