Comprehensive molecular characterization of gastric adenocarcinoma
2014· article· en· Nature· Medicine
aff
6,505
citations
Works
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Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden
2017· article· en· Genome Medicine· Medicine
aff
3,730
citations
Revised Bethesda Guidelines for Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) and Microsatellite Instability
2004· article· en· JNCI Journal of the National Cancer Institute· Medicine
aff
3,183
citations
Efficacy of Pembrolizumab in Patients With Noncolorectal High Microsatellite Instability/Mismatch Repair–Deficient Cancer: Results From the Phase II KEYNOTE-158 Study
2019· article· en· Journal of Clinical Oncology· Medicine
aff
2,963
citations
Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer
2003· article· en· New England Journal of Medicine· Medicine
aff
2,150
citations
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
2006· article· en· Nature Genetics· Medicine
affno abstract
1,985
citations
Tumor Microsatellite Instability and Clinical Outcome in Young Patients with Colorectal Cancer
2000· article· en· New England Journal of Medicine· Medicine
aff
1,395
citations
Classification of colorectal cancer based on correlation of clinical, morphological and molecular features
2006· review· en· Histopathology· Medicine
aff
1,386
citations
Phase II Open-Label Study of Pembrolizumab in Treatment-Refractory, Microsatellite Instability–High/Mismatch Repair–Deficient Metastatic Colorectal Cancer: KEYNOTE-164
2019· article· en· Journal of Clinical Oncology· Medicine
aff
1,014
citations
Aspirin Use, TumorPIK3CAMutation, and Colorectal-Cancer Survival
2012· article· en· New England Journal of Medicine· Medicine
fundno aff
838
citations
Comprehensive Analysis of Hypermutation in Human Cancer
2017· article· en· Cell· Biochemistry, Genetics and Molecular Biology
afffundno abstract
796
citations
BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum
2004· article· en· Gut· Medicine
aff
724
citations
Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas
2018· article· en· Cancer Cell· Medicine
affno abstract
710
citations
Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum
2012· article· en· Gut· Medicine
fundno aff
609
citations
Difference Between Left-Sided and Right-Sided Colorectal Cancer: A Focused Review of Literature
2018· review· en· Gastroenterology Research· Medicine
venueno aff
574
citations
Relationships Between Immune Landscapes, Genetic Subtypes and Responses to Immunotherapy in Colorectal Cancer
2020· review· en· Frontiers in Immunology· Medicine
afffund
561
citations
DNA Mismatch Repair Status and Colon Cancer Recurrence and Survival in Clinical Trials of 5-Fluorouracil-Based Adjuvant Therapy
2011· article· en· JNCI Journal of the National Cancer Institute· Medicine
aff
529
citations
Pembrolizumab in Patients With Microsatellite Instability–High Advanced Endometrial Cancer: Results From the KEYNOTE-158 Study
2022· article· en· Journal of Clinical Oncology· Medicine
aff
498
citations
Molecular Classification and Correlates in Colorectal Cancer
2007· review· en· Journal of Molecular Diagnostics· Medicine
fundno affno abstract
461
citations
Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers
2008· article· en· Proceedings of the National Academy of Sciences· Medicine
afffund
447
citations
Pembrolizumab in microsatellite instability high or mismatch repair deficient cancers: updated analysis from the phase II KEYNOTE-158 study
2022· article· en· Annals of Oncology· Medicine
affno abstract
445
citations
Lymphocytic Reaction to Colorectal Cancer Is Associated with Longer Survival, Independent of Lymph Node Count, Microsatellite Instability, and CpG Island Methylator Phenotype
2009· article· en· Clinical Cancer Research· Medicine
fundno aff
419
citations
Colorectal Carcinoma: Diagnostic, Prognostic, and Molecular Features
2003· review· en· Modern Pathology· Medicine
affno abstract
408
citations
Effect of Combined Immune Checkpoint Inhibition vs Best Supportive Care Alone in Patients With Advanced Colorectal Cancer
2020· article· en· JAMA Oncology· Medicine
affabout
398
citations
Colon Cancer Family Registry: An International Resource for Studies of the Genetic Epidemiology of Colon Cancer
2007· article· en· Cancer Epidemiology Biomarkers & Prevention· Medicine
aff
397
citations