967
citations
Works
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293 workspage 1 of 12
Minimum Information about a Biosynthetic Gene cluster
2015· article· en· Nature Chemical Biology· Medicine
afffundno abstract
908
citations
The promise and peril of chemical probes
2015· article· en· Nature Chemical Biology· Chemistry
afffund
850
citations
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
2012· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
afffundno abstract
825
citations
Making carbon-nitrogen bonds in biological and chemical synthesis
2006· review· en· Nature Chemical Biology· Chemistry
affno abstract
817
citations
Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
2020· article· en· Nature Chemical Biology· Medicine
afffundno abstract
714
citations
Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain
2014· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
afffundno abstract
708
citations
A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo
2008· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
afffundno abstract
704
citations
A new glucagon and GLP-1 co-agonist eliminates obesity in rodents
2009· article· en· Nature Chemical Biology· Medicine
affno abstract
634
citations
Mitochondrial metabolism promotes adaptation to proteotoxic stress
2019· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
affno abstract
623
citations
Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation
2012· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
afffundno abstract
615
citations
Immune modulation by multifaceted cationic host defense (antimicrobial) peptides
2013· review· en· Nature Chemical Biology· Immunology and Microbiology
affno abstract
601
citations
Rapid behavior-based identification of neuroactive small molecules in the zebrafish
2010· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
affno abstract
540
citations
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells
2011· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
afffundno abstract
531
citations
Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy
2011· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
afffundno abstract
521
citations
Target validation using chemical probes
2013· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
fundno affno abstract
435
citations
NMR spectroscopy brings invisible protein states into focus
2009· review· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
afffundno abstract
430
citations
Building a new conceptual framework for receptor heteromers
2009· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
afffundno abstract
392
citations
Mechanism-based corrector combination restores ΔF508-CFTR folding and function
2013· article· en· Nature Chemical Biology· Medicine
affno abstract
390
citations
An enzyme-coupled biosensor enables (S)-reticuline production in yeast from glucose
2015· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
affno abstract
386
citations
Targeting the disordered C terminus of PTP1B with an allosteric inhibitor
2014· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
affno abstract
383
citations
Seeing is believing
2013· letter· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
affno abstract
380
citations
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors
2016· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
fundno affno abstract
372
citations
Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A
2006· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
affno abstract
364
citations
An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells
2016· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
fundno affno abstract
357
citations