Dedication: Jim Orzechowski (1944–2003) and Michael Kiley (1942–2004)
Notice bibliographique
Résumé
This supplement to the Journal of Infectious Diseases is dedicated to the memories of Jim Orzechowski (1944–2003) and Michael Kiley (1942–2004), individuals who were instrumental in bringing biosafety level 4 (BSL4) biocontainment into the 21st century. Jim Orzechowski, a Canadian from the prairies of Manitoba, received a degree in architecture fromNorth Dakota State University in 1970, joined the architectural firm of Smith Carter, and, within 4 years, was a partner in the company. Beginning in 1978, Smith Carter began designing medical structures, and, in 1987, Jim led a consortium that won the bid to build new laboratories for Canada's health and agriculture ministries. Patient and always careful, the team took more than 5 years to design what has become the prototype for modern BSL4 laboratories. The Canadian Science Centre for Human and Animal Health (CSCHAH) was dedicated in 1999 and has already contributed major new knowledge to high-containment biomedical science. Jim's company now designs BSL4 laboratories in the United States and beyond. Michael Kiley was born in Saratoga Springs, New York. His dad was a physician from a family with longstanding ties to Notre Dame University. After graduating from that institution, Mike earned a Ph.D. at the University of Virginia and eventually joined the Special Pathogens Branch at the Centers for Disease Control and Prevention (CDC) as a young molecular virologist. He performed some of the first molecular work ever in the positive-pressure “space suit” mode. The subjects were Ebola and Marburg viruses. Mike became client representative during construction of Building 15 at the CDC in the mid-1980s and then moved to the National Institutes of Health (NIH) as a biosafety expert. During that time, he joined 2 other colleagues to provide scientific and containment review as design proceeded for the CSCHAH, and he finally left the NIH to work full time in Winnipeg as plans were finalized and construction began. At the time of his death, Mike was chief biosafety officer for the US Department of Agriculture. These men have left a visible, poignant legacy that shall endure for many decades. We shall not see their like again. Supplement sponsorship. This article was published as part of a supplement entitled “Filoviruses: Recent Advances and Future Challenges,” sponsored by the Public Health Agency of Canada, the National Institutes of Health, the Canadian Institutes of Health Research, Cangene, CUH2A, Smith Carter, Hemisphere Engineering, Crucell, and the International Centre for Infectious Diseases. Jim Orzechowski Michael Kiley
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,004 | 0,022 |
| Méta-épidémiologie (sens strict) | 0,001 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,001 | 0,001 |
| Études des sciences et des technologies | 0,002 | 0,001 |
| Communication savante | 0,004 | 0,002 |
| Science ouverte | 0,002 | 0,004 |
| Intégrité de la recherche | 0,002 | 0,005 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,167 | 0,102 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».